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Real-world evidence in gynecologic cancers presented at key oncology conferences in the United States: Distribution and factors related to high-tier acceptance

Elizabeth A Szamreta, Mansi Modi, Ramu Periyasamy, Bhavani Yamsani, Pattabhi Machiraju, Neetu Menghani and Matthew Monberg

PLOS ONE, 2025, vol. 20, issue 4, 1-15

Abstract: Purpose: To describe the distribution, trends, and characteristics of types of real-world evidence (RWE) abstracts presented at key oncology congresses. Methods: Data on gynecologic cancers (cervical, ovarian, endometrial, and multiple gynecologic/other) were extracted from the American Society of Clinical Oncology (ASCO) and the Society of Gynecologic Oncology (SGO) conference databases (2018–2020) to: a) identify the proportion of clinical trial (CT) versus RWE abstracts accepted; b) describe the distribution and tier of acceptance of RWE versus CTs; c) analyze the characteristics (authorship, data source, data type, study design, outcome[s], and presence of statistically significant results) associated with RWE acceptance. Results: Of 3163 abstracts screened, 2271 (77% RWE, 23% CTs) were included. RWE represented a higher proportion of work at SGO versus ASCO (70% vs 30%). Overall, more RWE studies versus CTs were accepted as posters (75% vs 60%), while fewer were accepted as oral presentations (4% vs 20%; p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0321654

DOI: 10.1371/journal.pone.0321654

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