Association between nurses’ knowledge and attitudes and caring behaviors toward people with opioid use disorder

Inyene Edem Essien-Aleksi, Yuan Zhang, Don Roosan, Tracie McPadden, Leslie Rideout, Michael Martin, Paula-Jo Beniers, Amy Lund, Danielle Leone-Sheehan and Alysse Wurcel

PLOS ONE, 2026, vol. 21, issue 3, 1-15

Abstract: Background: Hospital nurses are crucial in inpatient OUD care, but knowledge gaps and negative attitudes may affect care quality. Few studies have examined the relationship between nurses’ knowledge and attitudes and their caring behaviors toward patients with OUD in hospital settings. Method: We conducted a descriptive, exploratory cross-sectional study among hospital nurses at two northeast U.S hospitals. To explore nurses’ perspectives, we used validated instruments to assess knowledge and attitudes [DDPPQ] and caring behaviors [CBI-6]. DDPPQ and CBI-6 scores were treated as ordinal composite measures and summarized using medians and interquartile ranges. Group differences were examined across demographic and work-related factors using Mann–Whitney U and Kruskal–Wallis tests. Associations between DDPPQ and CBI-6 scores were analyzed using Spearman’s rank correlation with bootstrapped confidence intervals. Median (quantile) regression (τ = 0.50) was used to assess adjusted associations. Results: A total of 125 nurses completed the survey. Most nurses were female (94%), white (82%), and employed full-time (87%). Higher DDPPQ scores, indicating lower knowledge and more negative attitudes, differed by years of experience and hospital site. CBI-6 scores varied by shift type, with permanent night-shift nurses reporting the highest median caring behaviors. Higher DDPPQ scores were significantly associated with lower caring behaviors (ρ = –0.42; 95% CI: –0.52 to –0.30; p

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0325874

DOI: 10.1371/journal.pone.0325874

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