Advanced MDCT assessment of abdominal aortic wall integrity and morphometry in the Saudi cohort: A single-centre cross-sectional study

Mohammad Ahmad Mostafa Alloush, Mazin Babikir Hassib, Husain Alturkistani, Rafat S Mohtasib, Rashed Ali Alhamed, Reham Mukhlid Almutairi and Mohammed J Alsaadi

PLOS ONE, 2025, vol. 20, issue 8, 1-11

Abstract: Background: Accurate reference values for abdominal aortic dimensions and wall thickness are crucial for the early detection and management of vascular diseases, particularly abdominal aortic aneurysms (AAAs). However, there is a lack of population-specific normative data for the Saudi population. Methods: A cross-sectional study was conducted on 347 adults [111 males, 236 females] aged 20–80 at King Fahad Medical City. Multidetector computed tomography (MDCT) was utilised to measure the abdominal aortic lumen area, diameter, and wall thickness at three standard anatomical levels. Pixel-based segmentation and image analysis using MATLAB allowed for precise quantification of wall thickness. Multiple linear regression was employed to assess associations with age, gender, and BMI. Results: The average diameter of the aorta was 1.87 cm, the average wall thickness was 1.6 mm, and the average lumen area was 3.01 cm². Males generally had thicker aortic walls and larger dimensions than females, particularly in younger age groups. However, these gender differences became less pronounced with older age and increased BMI. A higher BMI was strongly linked to thicker aortic walls (p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0329822

DOI: 10.1371/journal.pone.0329822

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