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Effect of exercise intensity on redox biomarkers in healthy adults: A systematic review and meta-analysis of randomized clinical trials

Flor Isela Torres-Rojo, Liliana Aracely Enríquez-del Castillo, Susana Aidée González-Chávez, Luis Alberto Flores-Olivares, Estefanía Quintana-Mendias and Claudia Esther Carrasco-Legleu

PLOS ONE, 2025, vol. 20, issue 8, 1-15

Abstract: Purpose: This meta-analysis aimed to establish the effect of vigorous and non-vigorous exercise interventions on biomarkers of redox status in healthy adults. Materials and methods: Based on the PRISMA guidelines, we searched the following databases: Scopus, Web of Science, PubMed, Springer, Science Direct, Cochrane Library, Dialnet, Redalyc, and Lilacs for randomized controlled clinical trials investigating the effect of non-vigorous and vigorous chronic exercise in healthy adults, with the evaluation of antioxidants. The quality of evidence and risk of biases were assessed using the PEDro scale and version 2 of the Cochrane tool for risk of bias assessment in randomized trials (RoB2). Results: Seven randomized clinical trials evaluating nine training protocols were included (n=267). Individual evaluations demonstrated an increase in antioxidant capacity (I2=0%, Z=4.56, p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0330185

DOI: 10.1371/journal.pone.0330185

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