Risk factors for mental disorders in pregnant women in two cities from São Paulo, Brazil: A cohort study

Audêncio Victor, Maria Paula de Carvalho Leitão, Lívia Patrícia Rodrigues Batista, Laisla de França da Silva Teles, Perla Pizzi Argentato, Liania A Luzia, Rinaldo Artes and Patrícia Helen Rondó

PLOS ONE, 2025, vol. 20, issue 9, 1-16

Abstract: Introduction: Mental disorders during pregnancy are a significant public health problem due to the substantial physiological and psychological changes that occur during this period. This study aims to investigate the risk factors for mental disorders in pregnant women by comparing data from two distinct cohorts in Jundiaí and Araraquara, Brazil. Methods: This is a prospective cohort study that included pregnant women from two Brazilian cohorts in São Paulo state. The Jundiaí cohort (1997–2000) included 865 pregnant women, while the Araraquara cohort (2017–2024) included 755 pregnant women. Socioeconomic, demographic, obstetric history, and mental health data were collected and analyzed. Mental health was assessed using standardized questionnaires, including the General Health Questionnaire (GHQ), the State-Trait Anxiety Inventory (STAI), Trait Anxiety Inventory (TAI) and the Perceived Stress Scale (PSS). Statistical analysis included bivariate tests and univariate and multivariate random-effects models for panel data. Results: Araraquara participants showed significantly higher GHQ scores at baseline (mean = 4.00) than Jundiaí (mean = 2.78; p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0330921

DOI: 10.1371/journal.pone.0330921

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