Dementia as a risk factor for 30-day mortality in community-acquired pneumonia in Colombia (CAP): A survival study

Juan Sebastian Hernández-Puentes, Alirio Rodrigo Bastidas-Goyes, Eduardo Tuta-Quintero, Diana Díaz-Quijano, Nicole Méndez Peñalosa, Nayah Zuleta Sanchez, María Herran Perez, Juan Rodríguez Sánchez, Valentina Ortiz Marquez, Ana Colmenares Leal, Juanita Zuleta Montañez, Laura Riveros Pedraza, Laura Sarmiento Cardozo, María Piñeros Clavijo, Maria Vasquez Bazurto and Isabella Lenhardt Guaqueta

PLOS ONE, 2025, vol. 20, issue 10, 1-10

Abstract: Background: Community-acquired pneumonia (CAP) represents a significant clinical challenge, particularly in patients with comorbidities, such as dementia, which increases the risk of mortality and hospitalization. Despite its relevance, dementia has not been considered a CAP severity assessment tool. Furthermore, there is limited information on this topic in Latin America. Therefore, this study aimed to analyze 30-day survival in patients with CAP and dementia in Colombia with the objective of identifying the impact of dementia on clinical outcomes and understanding this phenomenon in the region. Methods: A multicenter retrospective cohort study with survival analysis was conducted on patients with CAP admitted to two tertiary care institutions in Colombia between January 2010 and December 2020. Results: The study included 3,374 subjects: 354 (10.5%) with dementia and 3,020 (89.5%) without dementia. The mean age was 65.5 years, higher in the dementia group (82.5 vs. 63.5 years, p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0332713

DOI: 10.1371/journal.pone.0332713

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