Integrative GWAS and RNA-Seq analysis for target identification and virtual drug screening in colorectal cancer

Qinghui Liu, Yiyang Lei, Zixuan Liu and Jiale Han

PLOS ONE, 2025, vol. 20, issue 10, 1-13

Abstract: Background: Colorectal cancer (CRC) is a leading cause of global cancer-related mortality, necessitating the identification of novel therapeutic targets. Integrating genetic and transcriptomic data may reveal key molecular drivers of CRC progression and treatment opportunities. Methods: We performed a multiomics analysis combining genome-wide association study (GWAS) data (p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0333179

DOI: 10.1371/journal.pone.0333179

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