Development of guidelines for managing unused and expired medications in local communities: An engaged stakeholder waste hierarchy approach

Patranit Srijuntrapun and Kusawadee Maluangnon

PLOS ONE, 2026, vol. 21, issue 3, 1-18

Abstract: Objectives: The management of unused and expired medications is essential to address environmental pollution, ensure public health safety, and optimize healthcare resources. Proper disposal of medications is especially challenging in areas where there is a lack of organized take-back programs. To bridge this gap, this study aims to develop inclusive guidelines through collaborative stakeholder engagement, while recognizing the absence of universally applicable solutions. Methods: The study uses a mixed-methods approach, relying on surveys, in-depth interviews, and focus groups. First, 156 households were surveyed to measure the amount and economic value of unused and expired medications in their possession. Subsequently, in-depth interviews were conducted with 45 participants, including healthcare professionals, community leaders, citizens, and policymakers. These in-depth interviews provided rich insights about the roles, local contexts, and challenges regarding the management of unused and expired medications. Lastly, focus group discussions with 16 participants provided the basis for the development of a new set of guidelines aligned with waste hierarchy principles and founded on a holistic view of the medication cycle, from acquisition to disposal. Results: The findings of the study have revealed that blood glucose lowering agents are the most common type of unused medication kept by households, while anti-hypertensive drugs are the ones that most frequently expire. In addition, the study has shown that medication wastage occurs at multiple stages across the system. Building on these insights, a set of guidelines and community-based management pathways were developed, offering a practical and scalable model in seven steps that can be applied to environments with no formal take-back systems. Conclusions: The guidelines presented in this study offer a practical and effective framework for policymakers, researchers, and practitioners focused on regions that lack formal disposal mechanisms to guide community-based medication wastage reduction and disposal practices, supporting the sustainable production and consumption of medications.

Date: 2026
References: Add references at CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0343225 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 43225&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0343225

DOI: 10.1371/journal.pone.0343225

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().