Structure function relationships differ between optic neuritis and glaucoma with comparable optical coherence tomography findings

Heesuk Kim, Mi Jeong Kim, Jihei Sara Lee, Chan Yun Kim and Hyoung Won Bae

PLOS ONE, 2026, vol. 21, issue 7, 1-16

Abstract: This retrospective study compared structure-function relationships between patients with optic neuritis (ON) and primary open-angle glaucoma (POAG), focusing on the extent of retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) damage and its correlation with visual field (VF) defects. We included 194 patients (ON: 47; POAG: 147) referred to Yonsei University Severance Eye Hospital between 2017 and 2023. RNFL and GCIPL thickness, VF indices, and the relationship between structural and functional measures were assessed. Despite comparable RNFL and GCIPL thinning, ON demonstrated significantly better VF performance than POAG (mean deviation: −2.26 dB vs. −7.32 dB; VF index: 95.48% vs. 80.43%; both p

Date: 2026
References: Add references at CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0353553 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 53553&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0353553

DOI: 10.1371/journal.pone.0353553

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().