Caregiver burden and its association with depression, anxiety, and quality of life among caregivers of individuals with severe persistent mental illness in Saudi Arabia: A cross-sectional study

Fatimah Albrekkan, Shuliweeh Alenezi, Ahmad Ghesheyan, Mohammed S Almousa, Mohammed A Alabduljabbar, Ibraheem M Alkanhal, Musaab A Alzuhair and Ibrahim E Alahmadi

PLOS ONE, 2026, vol. 21, issue 8, 1-14

Abstract: Caregivers of patients with Severe Persistent Mental Illness (SPMI) face tremendous challenges. They often experience elevated levels of burden, depression, and anxiety. These factors negatively impact their quality of life (QoL). However, few studies have examined caregiver burden and its psychological effects in Saudi Arabia. This study aims to assess caregiver burden in relation to socio-demographic characteristics and its correlation with depression, anxiety, and QoL. The study tool consisted of validated questionnaire, including the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), abridged Arabic version of the Zarit Burden Interview (ZBI), and the World Health Organization Quality of Life-Brief Version (WHOQOL-BREF). A cross-sectional convenience sample of 120 participants was recruited from the Psychiatry Outpatient Clinics at King Saud University Medical City in Riyadh, Saudi Arabia. Our results showed a significant positive correlation between caregiver burden and depression and anxiety scores (p

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0355872

DOI: 10.1371/journal.pone.0355872

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