Intrasubject Medication Adherence Patterns

Cynthia L. Russell, Vicki S. Conn, Catherine Ashbaugh, Richard Madsen, Karen Hayes and Gilbert Ross
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Cynthia L. Russell: University of Missouri-Columbia
Vicki S. Conn: University of Missouri-Columbia
Catherine Ashbaugh: University of Missouri-Columbia
Richard Madsen: University of Missouri-Columbia
Karen Hayes: Wichita State University
Gilbert Ross: University of Missouri-Columbia

Clinical Nursing Research, 2007, vol. 16, issue 2, 153-163

Abstract: The purpose of this prospective descriptive study was to explore the patterns of intrasubject (between medication) adherence of two similarly timed, twice-daily medications using the Medication Event Management System ® electronic monitoring cap. Medication adherence was measured for 6 months using electronic monitoring in 25 adult renal-transplant recipients. Data were available from 7,119 electronic medication events. Results indicated that two twice-daily medications scheduled to be taken simultaneously were taken within 5 min of each other 77% of the time and within 10 min, 92% of the time. When only the first scheduled dose of the day was examined, the results are 79% and 95%, respectively. These findings are important to researchers and clinicians who must evaluate medication adherence in transplant recipients while balancing cost and subject burden. This study provides empirical support for monitoring a single immunosuppressive medication electronically to estimate medication adherence with double or triple immunosuppressive drug therapy.

Keywords: medication adherence; transplantation; patterns (search for similar items in EconPapers)
Date: 2007
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Persistent link: https://EconPapers.repec.org/RePEc:sae:clnure:v:16:y:2007:i:2:p:153-163

DOI: 10.1177/1054773806296429

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