Exploration of Adherence to the Immunosuppressive Medication in Kidney Transplant Recipients Based on Theory of Planned Behavior

Luo Yang, Hong-xia Liu, Yue Hu, Bei Zhang, Fu-cong Peng, Chang-yun Wei and Rui-ting Wang

Clinical Nursing Research, 2022, vol. 31, issue 6, 1189-1198

Abstract: To investigate adherence to immunosuppressive medication (IM) in kidney transplant recipients (KTRs) and analyze the associated factors using the Theory of Planned Behavior (TPB). Data were collected at Time1 (T1) and 3 months later (T2). T1: the elements of the TPB, past behavior, beliefs about medicines, perceived social support were measured. T2: IM adherence was measured. Structural equation modeling was applied to analyze the associated factors of medication adherence. A total of 246 KTRs were included. The average IM adherence score of KTRs’ was 4.86 ( SD  = 1.63). Of the recipients, 39.43% had one aspect of non-adherence to IM. The model could explain 28.7% of the variance in adherence to IM ( R 2  = .287, p  = .006). TPB is a useful tool for understanding adherence to IM in KTRs. Caregivers can provide effective interventions during follow-up, which should focus on improving medication beliefs as well as provision of other external support especially from outside.

Keywords: kidney transplantation; medication adherence; theory of planned behavior; structural equation modeling (search for similar items in EconPapers)
Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:sae:clnure:v:31:y:2022:i:6:p:1189-1198

DOI: 10.1177/10547738221096550

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