Homozygous-Recessive Characteristics as a Biomarker of Predisposition for COVID-19

Darko GrujiÄ ić, Ljiljana Mirkov, Dragić Banković, Kristina Virijević, Dragoslav Marinković and Olivera MiloÅ¡ević-Djordjević

Clinical Nursing Research, 2023, vol. 32, issue 3, 589-600

Abstract: Coronavirus disease (COVID-19), a new form of severe acute respiratory syndrome, has caused a global pandemic. The aim of this study was to analyze homozygous-recessive characteristics (HRC) in the group of COVID-19 patients, considering their gender, forms of the disease (mild and severe symptoms), risk factors: hypertension, diabetes mellitus type 2, hyperlipidemia, smoking habits, and the distribution of ABO blood group. Using the HRC test, we analyzed 20 HRCs in a sample of 321 individuals: 205 patients and 116 controls. The average HRC in patients was significantly higher than controls, as well as in patients with severe symptoms compared to patients with mild symptoms. The patients with higher HRC (cut-off ≤5.5) experienced a significantly increased risk of disease of 2.3 times ( OR  = 2.315, p  

Keywords: COVID-19; homozygous-recessive characteristics; genetic predisposition (search for similar items in EconPapers)
Date: 2023
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.sagepub.com/doi/10.1177/10547738221147754 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:sae:clnure:v:32:y:2023:i:3:p:589-600

DOI: 10.1177/10547738221147754

Access Statistics for this article

More articles in Clinical Nursing Research
Bibliographic data for series maintained by SAGE Publications ().