Cognitive Function in Patients with Cushing Syndrome

Lorah D. Dorn and Paula Cerrone
Additional contact information
Lorah D. Dorn: University of Pittsburgh
Paula Cerrone: University of Pittsburgh

Clinical Nursing Research, 2000, vol. 9, issue 4, 420-440

Abstract: The purposes of this study were to examine the level of improvement of cognitive function 12 months posttreatment in adult patients with Cushing syndrome (CS), the relationships of cognitive function to duration of CS or recovery of the hypothalamic pituitary adrenal (HPA) axis, and depression and improved cognitive functioning. Thirty-three patients with CS and a matched comparison group were enrolled. IQ, depression, and endocrine factors were measured during the active phase of CS and at 12 months posttreatment for CS. Results show no group differences in cognitive function across time but a trend for CS patients to have lower IQ scores at baseline. Individual differences in performance were striking. For some subscales of IQ there was a positive relationship with recovery of the HPA axis and a negative relationship with duration of CS as well as an improvement if depression had decreased. Limitations of the study are cited along with clinical implications and directions for future research .

Date: 2000
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.sagepub.com/doi/10.1177/10547730022158672 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:sae:clnure:v:9:y:2000:i:4:p:420-440

DOI: 10.1177/10547730022158672

Access Statistics for this article

More articles in Clinical Nursing Research
Bibliographic data for series maintained by SAGE Publications ().