Current development status of iBNCT001, demonstrator of a LINAC-based neutron source for BNCT

Hiroaki Kumada, Yinuo Li, Kiyoshi Yasuoka, Fujio Naito, Toshikazu Kurihara, Takashi Sugimura, Masaharu Sato, Yoshitaka Matsumoto, Akira Matsumura, Hideki Sakurai and Takeji Sakae

Jadavpur Journal of International Relations, 2022, vol. 24, issue 3-4, 347-358

Abstract: The iBNCT project aims to develop “iBNCT001,†a demonstration device of the linac-based neutron irradiation facility for boron neutron capture therapy (BNCT) application. iBNCT001 generates an epithermal neutron beam by irradiating 8 MeV protons accelerated by a linac onto a beryllium target. Currently, the linac can drive an average proton current of 2.1 mA. Several experiments were performed using a water phantom to confirm the main physical characteristics of the neutron beam produced at the irradiation position. The measurement results demonstrated that the maximum thermal neutron flux achievable in the phantom volume was approximately 1.36 × 10 9 cm − 2 s − 1 when a normal beam collimator with a 120 mm diameter was used. This neutron beam intensity was sufficient to complete the irradiation within 30 min using the BNCT approach. In addition to normal beam collimators, extended collimators that protrude 100 mm from the wall were developed. By using an extended collimator, it is possible to prevent interference of the patient’s body with the wall when irradiating head and neck cancers. The measurement results for the extended collimator demonstrated that irradiation with the collimator could be completed within 1 h when the neutron beam is generated with an average proton current of 2.1 mA.

Keywords: Boron neutron capture therapy; LINAC; accelerator-based neutron source; phantom irradiation experiment (search for similar items in EconPapers)
Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:sae:jadint:v:24:y:2022:i:3-4:p:347-358

DOI: 10.3233/JNR-220029

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