Computational Control of an HIV Model

C. Myburgh () and K. Wong ()

Annals of Operations Research, 2005, vol. 133, issue 1, 277-283

Abstract: We consider a computational approach to solving an optimal control formulation of optimal drug scheduling in HIV infected individuals. The optimal control problem is transformed using the control parameterisation enhancing technique (CPET), which enables efficient computation of an optimal control using a relatively coarse discretisation. A number of numerical difficulties with the model are discussed, and for illustration, numerical examples are solved. Copyright Springer Science + Business Media, Inc. 2005

Keywords: optimal control; HIV; CPET (search for similar items in EconPapers)
Date: 2005
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DOI: 10.1007/s10479-004-5038-6

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