Applied Health Economics and Health Policy

2008 - 2025

Current editor(s): Timothy Wrightson

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Volume 21, issue 6, 2023

Challenges in the Evaluation of Emerging Highly Specialised Technologies: Is There a Role for Living HTA? pp. 823-830

Tracy Merlin, Jackie Street, Drew Carter and Hossein Haji Ali Afzali

Drug Repurposing of Generic Drugs: Challenges and the Potential Role for Government pp. 831-840

Karel H. Pol, Mohamad Aljofan, Olivier Blin, Jan H. Cornel, Gerard A. Rongen, Aurélie-Gaëlle Woestelandt and Michael Spedding

Economic Evaluations of Imaging Biomarker-Driven Companion Diagnostics for Cancer: A Systematic Review pp. 841-855

Sibo Liu, Daniel SW Tan, Nicholas Graves and Ann-Marie Chacko

Is Using Sodium-Glucose Cotransporter-2 Inhibitors to Treat Adults with Chronic Heart Failure Cost-Effective? A Systematic Review of Cost-Effectiveness Studies pp. 857-875

Yi Jing Tan, Siew Chin Ong and Ying Min Kan

Projected Impact on Labour Productivity Costs of Cancer-Related Premature Mortality in Europe 2018–2040 pp. 877-889

Marta Ortega-Ortega, Paul Hanly, Alison Pearce, Isabelle Soerjomataram and Linda Sharp

Evaluating the Short-Term Costs and Benefits of a Nationwide Diabetes Prevention Programme in England: Retrospective Observational Study pp. 891-903

Emma McManus, Rachel Meacock, Beth Parkinson and Matt Sutton

Prices of Orphan Drugs in Four Western European Countries Before and After Market Exclusivity Expiry: A Cross-Country Comparison of List Prices and Purchase Prices pp. 905-914

Aniek Dane, Anne-Sophie Klein Gebbink, Jan-Dietert Brugma, Albane Degrassat-Théas, Martin J. Hug, Morten B. Houlind, P. Paubel, P. Hugo M. Kuy and Carin A. Uyl- de Groot

Direct Medical Costs of COPD in the USA: An Analysis of the Medical Expenditure Panel Survey 2017–2018 pp. 915-924

Chintal H. Shah, Robert M. Reed, Linda Wastila, Eberechukwu Onukwugha, Mathangi Gopalakrishnan and Zafar Zafari

The Assessment of Patient-Reported Outcomes for the Authorisation of Medicines in Europe: A Review of European Public Assessment Reports from 2017 to 2022 pp. 925-935

Michela Meregaglia, Francesco Malandrini, Stefania Angelini and Oriana Ciani

Child–Parent Agreement in the Assessment of Health-Related Quality of Life Using the CHU9D and the PedsQLTM pp. 937-947

Diana Khanna, Jyoti Khadka, Christine Mpundu-Kaambwa and Julie Ratcliffe

Psychometric Evaluation of the PedsQL GCS and CHU9D in Australian Children and Adolescents with Common Chronic Health Conditions pp. 949-965

Rakhee Raghunandan, Kirsten Howard, Sarah Smith, Anagha Killedar, Erin Cvejic, Martin Howell, Stavros Petrou, Emily Lancsar, Germaine Wong, Jonathan Craig and Alison Hayes

Correction: Deterministic and Probabilistic Analysis of a Simple Markov Model: How Different Could They Be? pp. 967-967

Howard Thom

Volume 21, issue 5, 2023

Health Reform in Aotearoa New Zealand: Insights on Health Equity Challenges One Year On pp. 683-687

Paula Lorgelly and Daniel J. Exeter

myCOPD App for Managing Chronic Obstructive Pulmonary Disease: A NICE Medical Technology Guidance for a Digital Health Technology pp. 689-700

Heather Davies, Mary Chappell, Yingying Wang, Angaja Phalguni, Stephanie Wake, Mick Arber and Judith Shore

A Systematic Review of Cost-Effectiveness Analyses of Colorectal Cancer Screening in Europe: Have Studies Included Optimal Screening Intensities? pp. 701-717

Rajani Pokharel, Yi-Shu Lin, Ethna McFerran and James F. O’Mahony

The Economic Cost of Rising Non-communicable Diseases in India: A Systematic Literature Review of Methods and Estimates pp. 719-730

Varsha Shukla and Rahul Arora

Cost-Effectiveness of Anti-retroviral Adherence Interventions for People Living with HIV: A Systematic Review of Decision Analytical Models pp. 731-750

Ali Ahmed, Juman Abdulelah Dujaili, Lay Hong Chuah, Furqan Khurshid Hashmi, Long Khanh-Dao Le, Saval Khanal, Ahmed Awaisu and Nathorn Chaiyakunapruk

10 Years of AMNOG: What is the Willingness-to-Pay for Pharmaceuticals in Germany? pp. 751-759

Melanie Büssgen and Tom Stargardt

Symptomatic SARS-CoV-2 Episodes and Health-Related Quality of Life pp. 761-771

Caterina Alacevich, Inna Thalmann, Catia Nicodemo, Simon Lusignan and Stavros Petrou

Value for Money of CAR-T Cell Therapy for Patients with Diffuse Large B-cell Lymphoma in China: Evidence from a Cost-Effectiveness Analysis pp. 773-783

Weijia Wu, Yuping Zhou, Yannan Wang, Syed Afroz Keramat, Namal N. Balasooriya, Zixuan Zhao, Yi Yang, Tracy Comans and Hengjin Dong

Preferences for Enhanced Primary Care Services Among Older Individuals and Primary Care Physicians pp. 785-797

Semra Ozdemir, John Ansah and David Matchar

What About Offering a Financial Incentive Directly to Clinical Units to Encourage the Use of Biosimilars? Results of a Two-Year National Experiment in France pp. 799-811

Marion Tano, Pascal Paubel, Matthieu Ribault and Albane Degrassat-Théas

Values in Modelling: Video Series Development and Evaluation Survey pp. 813-820

Stephanie Harvard, Adam Easterbrook, Greg Werker, Alison McLean, Amin Adibi and David Murphy

Correction to: The False Economy of Seeking to Eliminate Delayed Transfers of Care: Some Lessons from Queueing Theory pp. 821-821

Richard M. Wood, Alison L. Harper, Zehra Onen-Dumlu, Paul G. Forte, Martin Pitt and Christos Vasilakis

Volume 21, issue 4, 2023

Health technology assessment – an important opportunity to inform the use of medical devices in the paediatric population: an analysis of NICE Medical Technology Guidance pp. 533-535

Sarah Greasley, Mark Campbell and James Wall

Review and Assessment of Policy Options for Improving Access to Combination Therapies in Oncology in Europe pp. 537-546

Christopher H. Henshall, Dávid Dankó, Leela Barham, Jaime Espín, Jorge Felix, Mary Harney, Peter Indra, Jorge Mestre-Ferrandiz, Gérard Pouvourville, Federico Spandonaro, Luka Vončina and Nils Wilking

How Much Should be Invested in Lung Care Across the WHO European Region? Applying a Monetary Value to Disability-Adjusted Life-Years Within the International Respiratory Coalition’s Lung Facts pp. 547-558

Matthew Franklin, Colin Angus, Tobias Welte and Guy Joos

Systematic Review of the Psychometric Performance of Generic Childhood Multi-attribute Utility Instruments pp. 559-584

Joseph Kwon, Sarah Smith, Rakhee Raghunandan, Martin Howell, Elisabeth Huynh, Sungwook Kim, Thomas Bentley, Nia Roberts, Emily Lancsar, Kirsten Howard, Germaine Wong, Jonathan Craig and Stavros Petrou

Modelling Methods of Economic Evaluations of HIV Testing Strategies in Sub-Saharan Africa: A Systematic Review pp. 585-601

Arthi Vasantharoopan, Victoria Simms, Yuyen Chan, Lorna Guinness and Hendramoorthy Maheswaran

Public Preferences for Introducing a COVID-19 Certificate: A Discrete Choice Experiment in the Netherlands pp. 603-614

J. Veldwijk, J. Exel, E. W. Bekker-Grob and N. Mouter

Modelled Distributional Cost-Effectiveness Analysis of Childhood Obesity Interventions: A Demonstration pp. 615-625

Anagha Killedar, Thomas Lung, Rachael W. Taylor and Alison Hayes

A Model-Based Estimate of the Cost-Effectiveness Threshold in Germany pp. 627-635

Afschin Gandjour

Budget Impact Analysis of the FreeStyle Libre Flash Continuous Glucose Monitoring System® in Patients with Type 1 Diabetes Mellitus and Type 2 Diabetes Mellitus with Multiple Daily Insulin Injections in Argentina pp. 637-650

Alfredo Palacios, Federico Rodriguez-Cairoli, Dario Balan, Carlos Rojas-Roque, Carolina Moreno-López, Barbara Braun, Federico Augustovski, Andrés Pichon-Riviere and Ariel Bardach

Exploring Consumer Preferences for Cannabis Vaping Products to Support Public Health Policy: A Discrete Choice Experiment pp. 651-659

Jennifer R. Donnan, Karissa Johnston, Michael Coombs, Maisam Najafizada and Lisa D. Bishop

Cost‑Effectiveness of Lorlatinib in First-Line Treatment of Adult Patients with Anaplastic Lymphoma Kinase (ALK)‑Positive Non‑Small‑Cell Lung Cancer in Sweden pp. 661-672

Jaesh Naik, Norma Beavers, Fredrik O. L. Nilsson, Laura Iadeluca and Chrissy Lowry

Conditional Funding Recommendations for Drugs in Canada: A Cross-Sectional Analysis pp. 673-681

Pooyeh Graili

Volume 21, issue 3, 2023

Global Pull Incentives for Better Antibacterials: The UK Leads the Way pp. 361-364

Kevin Outterson and John H. Rex

Can the UK ‘Netflix’ Payment Model Boost the Antibacterial Pipeline? pp. 365-372

Colm Leonard, Nick Crabb, David Glover, Sophie Cooper, Jacoline Bouvy, Milena Wobbe and Mark Perkins

The Broader Opportunity Costs in the Broader Cost-Effectiveness Analysis Framework pp. 373-384

Laura Vallejo-Torres

An Investigation into the Relationship Between Choice of Model Structure and How to Adjust for Subsequent Therapies Using a Case Study in Oncology pp. 385-394

Holly L. Cranmer, Gemma E. Shields and Ash Bullement

Stakeholder Engagement in the Development of Public Health Economic Models: An Application to Modelling of Minimum Unit Pricing of Alcohol in South Africa pp. 395-403

N. K. Gibbs, C. Angus, S. Dixon, C. D. H. Parry and P. S. Meier

Discrete Choice Experiments in Health State Valuation: A Systematic Review of Progress and New Trends pp. 405-418

Haode Wang, Donna L. Rowen, John E. Brazier and Litian Jiang

A Systematic Review of Health Economic Evaluations and Budget Impact Analyses to Inform Healthcare Decision-Making in Central America pp. 419-440

Carlos Rojas-Roque and Alfredo Palacios

The Impact of Value-Based Payment Models for Networks of Care and Transmural Care: A Systematic Literature Review pp. 441-466

Diogo L. L. Leao, Henricus-Paul Cremers, Dennis Veghel, Milena Pavlova and Wim Groot

Use of Decision-Analytic Modelling to Assess the Cost-Effectiveness of Diagnostic Imaging of the Spine, Shoulder, and Knee: A Scoping Review pp. 467-475

Sean Docking, Lan Gao, Zanfina Ademi, Christian Bonello and Rachelle Buchbinder

Medication Adherence and Healthcare Costs in Chronically Ill Patients Using German Claims Data pp. 477-487

Johannes Wendl, Andreas Simon, Martin Kistler, Jana Hapfelmeier, Antonius Schneider and Alexander Hapfelmeier

Cost Effectiveness of Denosumab for Secondary Prevention of Osteoporotic Fractures Among Postmenopausal Women in China: An Individual-Level Simulation Analysis pp. 489-499

Yawen Jiang, Shan Jiang, Limin Li, Si Shi, Mincai Li and Lei Si

The Impact of Suboxone’s Market Exclusivity on Cost of Opioid Use Disorder Treatment pp. 501-510

Meghan McGee, Kellia Chiu, Rahim Moineddin and Abhimanyu Sud

Economic Evaluation of Evusheld for Preexposure Prevention of COVID-19 in High-Risk Populations: Early Evidence from Thailand pp. 511-522

Waranya Rattanavipapong, Chittawan Poonsiri, Wanrudee Isaranuwatchai, Sopon Iamsirithaworn, Jutarat Apakupakul, Chaninan Sonthichai, Rungrueng Kitphati and Yot Teerawattananon

Measurement of Health-Related Quality of Life from Conception to Postpartum Using the EQ-5D-5L Among a National Sample of US Pregnant and Postpartum Adults pp. 523-532

Annette K. Regan, Pallavi Aytha Swathi, Marcianna Nosek and Ning Yan Gu

Volume 21, issue 2, 2023

Development of an Instrument for the Assessment of Health-Related Multi-sectoral Resource Use in Europe: The PECUNIA RUM pp. 155-166

Irina Pokhilenko, Luca M. M. Janssen, Aggie T. G. Paulus, Ruben M. W. A. Drost, William Hollingworth, Joanna C. Thorn, Sian Noble, Judit Simon, Claudia Fischer, Susanne Mayer, Luis Salvador-Carulla, Alexander Konnopka, Leona Hakkaart van Roijen, Valentin Brodszky, A-La Park and Silvia M. A. A. Evers

The Role of Mental Health on Workplace Productivity: A Critical Review of the Literature pp. 167-193

Claire Oliveira, Makeila Saka, Lauren Bone and Rowena Jacobs

Headroom Analysis for Early Economic Evaluation: A Systematic Review pp. 195-204

Esther A. Boudewijns, Thomas M. Otten, Mariam Gobianidze, Bram L. Ramaekers, Onno C. P. Schayck and Manuela A. Joore

Analysing the Efficiency of Health Systems: A Systematic Review of the Literature pp. 205-224

Rahab Mbau, Anita Musiega, Lizah Nyawira, Benjamin Tsofa, Andrew Mulwa, Sassy Molyneux, Isabel Maina, Julie Jemutai, Charles Normand, Kara Hanson and Edwine Barasa

The Cost-Effectiveness of Adjunctive Lifestyle Interventions for the Management of Cancer: A Systematic Review pp. 225-242

Andrew Gallagher, Violetta Shersher, Duncan Mortimer, Helen Truby and Terry Haines

The False Economy of Seeking to Eliminate Delayed Transfers of Care: Some Lessons from Queueing Theory pp. 243-251

Richard M. Wood, Alison L. Harper, Zehra Onen-Dumlu, Paul G. Forte, Martin Pitt and Christos Vasilakis

A Guideline-Implementation Intervention to Improve the Management of Low Back Pain in Primary Care: A Difference-in-Difference-in-Differences Analysis pp. 253-262

Ross Wilson, Yana Pryymachenko, J. Haxby Abbott, Sarah Dean, James Stanley, Sue Garrett, Fiona Mathieson, Anthony Dowell and Ben Darlow

An Economic Model for Estimating Trial Costs with an Application to Placebo Surgery Trials pp. 263-273

Chris Schilling, Michelle Tew, Samantha Bunzli, Cade Shadbolt, L. Stefan Lohmander, Zsolt J. Balogh, Francesco Paolucci, Peter F. Choong, Michelle M. Dowsey and Philip Clarke

Population-Level Impact of Omitting Axillary Lymph Node Dissection in Early Breast Cancer Women: Evidence from an Economic Evaluation in Germany pp. 275-287

Hoa Thi Nguyen, Manuela Allegri, Jörg Heil and André Hennigs

EQ-5D-5L Population Norms for Italy pp. 289-303

Michela Meregaglia, Francesco Malandrini, Aureliano Paolo Finch, Oriana Ciani and Claudio Jommi

The Value of New: Consideration of Product Novelty in Health Technology Assessments of Pharmaceuticals pp. 305-314

Patricia G. Synnott, Dominic Voehler, Daniel E. Enright, Stacey Kowal and Daniel A. Ollendorf

Cost-Effectiveness and Value of Information Analysis of an Ambient Intelligent Geriatric Management (AmbIGeM) System Compared to Usual Care to Prevent Falls in Older People in Hospitals pp. 315-325

Clarabelle T. Pham, Renuka Visvanathan, Mark Strong, Edward C. F. Wilson, Kylie Lange, Joanne Dollard, Damith Ranasinghe, Keith Hill, Anne Wilson and Jonathan Karnon

An Item-Response Mapping from General Health Questionnaire Responses to EQ-5D-3L Using a General Population Sample from England pp. 327-346

Edward J. D. Webb

A Comparative Analysis of Anticancer Drug Appraisals Including Managed Entry Agreements in South Korea and England pp. 347-359

Iyn-Hyang Lee, Karen Bloor and Eun-Young Bae

Volume 21, issue 1, 2023

Family Spillover Effects: Are Economic Evaluations Misrepresenting the Value of Healthcare Interventions to Society? pp. 5-10

Ashley A. Leech, Pei-Jung Lin, Brittany D’Cruz, Susan K. Parsons and Tara A. Lavelle

Development of a Health Technology Assessment Quality Appraisal Checklist (HTA-QAC) for India pp. 11-22

Yashika Chugh, Pankaj Bahuguna, Aamir Sohail, Kavitha Rajsekar, V. R. Muraleedharan and Shankar Prinja

Exploring the Integration of Environmental Impacts in the Cost Analysis of the Pilot MEL-SELF Trial of Patient-Led Melanoma Surveillance pp. 23-30

Jake T. W. Williams, Katy J. L. Bell, Rachael L. Morton and Mbathio Dieng

Valuation of Costs in Health Economics During Financial and Economic Crises: A Case Study from Lebanon pp. 31-38

Jalal Dahham, Ingrid Kremer, Mickaël Hiligsmann, Kamal Hamdan, Abdallah Nassereddine, Silvia M. A. A. Evers and Rana Rizk

A Systematic Review of Kidney Transplantation Decision Modelling Studies pp. 39-51

Mohsen Yaghoubi, Sonya Cressman, Louisa Edwards, Steven Shechter, Mary M. Doyle-Waters, Paul Keown, Ruth Sapir-Pichhadze and Stirling Bryan

Economic Evaluations of Preventive Interventions for Dental Caries and Periodontitis: A Systematic Review pp. 53-70

Tan Minh Nguyen, Utsana Tonmukayakul, Long Khanh-Dao Le, Hanny Calache and Cathrine Mihalopoulos

Determinants of COVID-19 Vaccine Rollouts and Their Effects on Health Outcomes pp. 71-89

Pragyan Deb, Davide Furceri, Daniel Jiménez, Siddharth Kothari, Jonathan Ostry and Nour Tawk

What Features of Fertility Treatment do Patients Value? Price Elasticity and Willingness-to-Pay Values from a Discrete Choice Experiment pp. 91-107

Elena Keller, Willings Botha and Georgina M. Chambers

Economic Effects of Fixed-Dose Versus Loose-Dose Combination Therapy for Type 2 Diabetes Patients pp. 109-118

Anna-Katharina Böhm, Udo Schneider and Tom Stargardt

Determining What Represents Value in the Treatment of Refractory or Unexplained Chronic Cough from the Perspective of Key Stakeholders in Spain Using Multi-Criteria Decision Analysis pp. 119-130

Christian Domingo, Mario Fernandez, Noe Garin, Javier Milara, Ignacio Moran, Irantzu Muerza, Adalberto Pacheco, Carlos Teruel, Roy Bentley, Rafael Subiran and Alicia Gil

Financing Comprehensive Immunization Services in Lao PDR: A Fiscal Space Analysis From a Public Policy Perspective pp. 131-140

Pankaj Bahuguna, Emiko Masaki, Gursimer Jeet and Shankar Prinja

Cost Effectiveness of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Patients with Knee Osteoarthritis pp. 141-152

Kangho Suh, Brian J. Cole, Andreas Gomoll, Seung-Mi Lee, Hangseok Choi, Chul-Won Ha, Hong Chul Lim, Myung Ku Kim, Gwi-Yeom Ha and Dong-Churl Suh

Correction to: Cost Effectiveness of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Patients with Knee Osteoarthritis pp. 153-153

Kangho Suh, Brian J. Cole, Andreas Gomoll, Seung-Mi Lee, Hangseok Choi, Chul-Won Ha, Hong Chul Lim, Myung Ku Kim, Gwi-Yeom Ha and Dong-Churl Suh