Quality of Life Predicts Survival and Hospitalisation in a Heart Failure Portuguese Population

Sónia Ramos (), Joana Prata, Francisco Rocha-Gonçalves, Paulo Bettencourt and Rui Coelho
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Sónia Ramos: University of Porto
Joana Prata: University of Porto
Francisco Rocha-Gonçalves: University of Porto
Paulo Bettencourt: University of Porto
Rui Coelho: University of Porto

Applied Research in Quality of Life, 2017, vol. 12, issue 1, No 3, 35-48

Abstract: Abstract The aim of this study was to examine whether quality of life (QoL) is an independent predictor of death and hospitalization for cardiovascular (CV) causes in patients with heart failure (HF). A 6- year prospective study was conducted on 130 outpatients with HF who were recruited from a cardiology service at S. João Hospital. Generic QoL was measured with the Medical Outcome Study 36-item Short Form Survey (SF-36), disease-specific QoL was measured with the Kansas City Cardiomyopathy Questionnaire (KCCQ) and the Beck Depression Inventory Scale (BDI-II) was used to screen for depressive symptoms (DS). Logistic regression and multinomial logistic regression analysis were used to evaluate the independent prognostic value of QoL measures on all cause mortality and hospitalization for CV causes after adjustment for clinical risk factors. During the follow-up 48 % of the participants died for all causes and 38 % were hospitalized for CV causes. Both generic and disease-specific QoL instruments were predictive of mortality and hospitalization on univariate analysis. After adjustment for prognostic factors such as DS, age, gender, B-type natriuretic peptide (BNP) levels, renal insufficiency and functional class NHYA only the summary clinical domain of KCCQ remained predictive of mortality. With respect to hospitalization for CV causes remained the predictive power: the summary clinical domain and the self-efficacy domains of KCCQ and the physical health domain of SF-36. Worse QoL is associated with all- cause death and hospitalization for CV causes in patients with HF and its impact persists over 6 years.

Keywords: Quality of life; Depressive symptoms; Mortality; Hospitalizations; Heart failure (search for similar items in EconPapers)
Date: 2017
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DOI: 10.1007/s11482-016-9449-8

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