Measuring Regional Variations in US Population-Level Health-Related Quality of Life During COVID-19 Using the EQ-5D-5L

Nadine K. Zawadzki (), Feng Xie, Seth A. Seabury, John A. Romley, D. Steven Fox, Cynthia L. Gong, Roy S. Zawadzki, Xiayu Jiao and Ning Yan Gu
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Nadine K. Zawadzki: University of Southern California
Feng Xie: McMaster University
Seth A. Seabury: University of Southern California
John A. Romley: University of Southern California
D. Steven Fox: University of Southern California
Cynthia L. Gong: Fetal and Neonatal Institute, Children’s Hospital Los Angeles
Roy S. Zawadzki: University of California
Xiayu Jiao: University of Southern California
Ning Yan Gu: University of San Francisco

Applied Research in Quality of Life, 2025, vol. 20, issue 2, No 7, 589-618

Abstract: Abstract Regional variations in coronavirus disease 2019 (COVID-19) suggest non-uniform impacts on health-related quality-of-life (HRQoL) across the US. This study measured regional variations in US population-level HRQoL during COVID-19. HRQoL was measured by the EQ-5D-5L in a three-wave cross-sectional online survey (spring 2020, summer 2020, winter 2021). Adjusted likelihood of any problems in EQ-5D-5L domains and adjusted mean utility and EQ-VAS were estimated and compared between US Census Bureau-designated region-divisions and waves. Regional variations were significant (p

Keywords: Health-related quality-of-life; COVID-19; EQ-5D; Population monitoring; Regional variation (search for similar items in EconPapers)
Date: 2025
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DOI: 10.1007/s11482-025-10427-z

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