Technologies to Improve Immunisation Safety

C. John Clements, Maria Teresa Aguado and Luis Jódar
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C. John Clements: World Health Organization
Maria Teresa Aguado: World Health Organization
Luis Jódar: World Health Organization

Drug Safety, 2001, vol. 24, issue 14, No 1, 1019-1026

Abstract: Abstract Ever since a vaccine was first used against smallpox, adverse events following immunisation have been reported. Adverse reactions may be caused by a fault in vaccine production, idiosyncratic responses or unsafe handling and vaccine administration practices. Technological advances that promise to bypass many of the dangers currently associated with vaccine administration are described. Plans for the next decade and beyond include developing injection-free systems for vaccine delivery that overcome the limitations of current immunisation programmes and help prevent programmatic mistakes. Also under development are new parenteral administration devices such as the auto-disable syringe and the mono-dose prefilled device, and mucosal and transcutaneous immunisation systems. Training needs to be at the forefront of efforts to limit human error. Above all, there must be a willingness to respond to new climates and new technologies in order to ensure safe immunisation of children globally.

Keywords: Injection Device; Paralytic Poliomyelitis; Yellow Fever Vaccine; Multivalent Vaccine; Tetanus Toxoid Vaccine (search for similar items in EconPapers)
Date: 2001
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DOI: 10.2165/00002018-200124140-00001

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