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Healthcare Databases for Drug Safety Research: Data Validity Assessment Remains Crucial

Nigel S. B. Rawson () and Carl D’Arcy
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Nigel S. B. Rawson: Eastlake Research Group
Carl D’Arcy: University of Saskatchewan

Drug Safety, 2018, vol. 41, issue 9, No 1, 829-833

Abstract: Abstract Administrative healthcare utilization databases are frequently used either individually or as a component of aggregated data for evaluating drug safety issues without taking into account their known deficiencies. All too often insufficient evidence is provided about their validity for the purposes for which they are used. The assessment of data validity is a key constituent that should be included in drug safety research studies and should take a broad multifaceted approach that encompasses both diagnostic and drug exposure data. Drug safety researchers need to continue advancing their knowledge of the data resources they use and to ensure that they and the users of their research understand the limitations of the data that are the foundation on which their research is built. Fundamental issues regarding data validity should be addressed in each use of administrative data for drug safety research.

Date: 2018
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DOI: 10.1007/s40264-018-0673-z

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