Immune stimulation in fish and chicken through weak low frequency electromagnetic fields

J. J. M. Cuppen (), G. F. Wiegertjes, H. W. J. Lobee, H. F. J. Savelkoul, M. A. Elmusharaf, A. C. Beynen, H. N. A. Grooten and W. Smink
Additional contact information
J. J. M. Cuppen: Immunent BV
G. F. Wiegertjes: Wageningen University
H. W. J. Lobee: Immunent BV
H. F. J. Savelkoul: Wageningen University
M. A. Elmusharaf: Utrecht University
A. C. Beynen: Utrecht University
H. N. A. Grooten: FIS BV
W. Smink: FIS BV

Environment Systems and Decisions, 2007, vol. 27, issue 4, 577-583

Abstract: Abstract A hypothesis is proposed how Low Frequency Electromagnetic Field (LF EMF) exposure can stimulate an immune response, based on recent insights in immunology. We hypothesize that the Immunent EMF treatment induces mild stress to cells, which then produce cytokines that function as alarms or so called danger signals for the immune system. In this way EMF treatment takes the place of multiplying pathogens, and the damage these cause, in the triggering of an immune response. In a first series of experiments in␣vitro common carp head kidney-derived phagocytes were used to determine ROS production as a measure for immune activation. Exposure to LF EMF signals (200–5,000 Hz) at 5 μT or 1.5 mT led to 42 or 33% increase in immune activity, respectively, compared to negative control values. EMF could also additionally stimulate chemically pre-stimulated samples up to 18% (5 μT) or 22% (1.5 mT). Significance of increase in ROS production in the total series was: p

Keywords: Immune stimulation; EMF; ELF; Electromagnetic fields; Feed conversion (search for similar items in EconPapers)
Date: 2007
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DOI: 10.1007/s10669-007-9055-2

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