Influence of static magnetic fields on nerve regeneration in vitro

Betty F. Sisken (), Paul Midkiff, Andrew Tweheus and Marko Markov
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Betty F. Sisken: University of Kentucky
Paul Midkiff: University of Kentucky
Andrew Tweheus: University of Kentucky
Marko Markov: Research International

Environment Systems and Decisions, 2007, vol. 27, issue 4, 477-481

Abstract: Abstract Our research involves determining how non-invasive electric and magnetic fields influence neuronal growth in vitro. In previous studies we have shown that pulsed electromagnetic fields (PEMF) as well as direct current (DC) alone stimulate neurite outgrowth from dorsal root ganglion explants [Sisken et al. 1984; Sisken et al. (Restor Neurol Neurosci 1:303–309, 1990); Greenebaum et al. (Bioelectromagnetics 17:293–302, 1996)]. A maximum response was obtained when nerve growth factor (NGF) was also present in the medium. The results of our experiments using static magnetic fields of different strengths are presented below and indicate that fields of high magnetic strength (450–900 gauss) with added NGF stimulate neurite outgrowth comparable to the response obtained with PEMF plus NGF.

Keywords: Neurite outgrowth; Nerve growth factor; Growth quantitation (search for similar items in EconPapers)
Date: 2007
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Citations: View citations in EconPapers (1)

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DOI: 10.1007/s10669-007-9117-5

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