Exploring the relationship between EQ-5D, DLQI and PASI, and mapping EQ-5D utilities: a cross-sectional study in psoriasis from Hungary

Emese Herédi, Fanni Rencz, Orsolya Balogh, László Gulácsi, Krisztina Herszényi, Péter Holló, Hajnalka Jókai, Sarolta Kárpáti, Márta Péntek, Éva Remenyik, Andrea Szegedi and Valentin Brodszky
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Emese Herédi: University of Debrecen
Fanni Rencz: Corvinus University of Budapest
Orsolya Balogh: Corvinus University of Budapest
László Gulácsi: Corvinus University of Budapest
Krisztina Herszényi: Semmelweis University
Péter Holló: Semmelweis University
Hajnalka Jókai: Semmelweis University
Sarolta Kárpáti: Semmelweis University
Márta Péntek: Corvinus University of Budapest
Éva Remenyik: University of Debrecen
Andrea Szegedi: University of Debrecen

The European Journal of Health Economics, 2014, vol. 15, issue 1, No 13, 119 pages

Abstract: Abstract Background There is a growing interest in policy making for using utility measures and identifying algorithms to convert disease-specific measures into utilities. Objectives To analyse the relationship between EQ-5D, Dermatology Life Quality Index (DLQI) and Psoriasis Area and Severity Index (PASI) in psoriasis. To transform DLQI scores, and key clinical, demographic and health service utilisation variables into utilities. Methods A cross-sectional questionnaire survey of 200 consecutive adult patients with moderate to severe psoriasis was carried out in two Hungarian university clinics. The relationship between the outcome measures were analysed with correlations and with the known-groups method. Bivariate and multivariate regression algorithms on EQ-5D scores were formulated. Results The mean age of respondents was 51 years (SD = 12.9), 68.5 % were male, and 51.5 % received biological therapy. Median EQ-5D, DLQI, and PASI scores were 0.73, 3.0, and 3.45, respectively. EQ-5D showed a moderate correlation with the DLQI and with the PASI (r s = −0.48 and −0.43, p

Keywords: Psoriasis; Quality of life; EQ-5D; DLQI; Mapping (search for similar items in EconPapers)
JEL-codes: I19 (search for similar items in EconPapers)
Date: 2014
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DOI: 10.1007/s10198-014-0600-x

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