Cost-of-illness studies in nine Central and Eastern European countries

Valentin Brodszky, Zsuzsanna Beretzky, Petra Baji, Fanni Rencz, Márta Péntek, Alexandru Rotar, Konstantin Tachkov, Susanne Mayer, Judit Simon, Maciej Niewada, Rok Hren and László Gulácsi
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Zsuzsanna Beretzky: Corvinus University of Budapest
Fanni Rencz: Corvinus University of Budapest
Márta Péntek: Corvinus University of Budapest
Alexandru Rotar: University of Amsterdam
Konstantin Tachkov: Medical University of Sofia
Susanne Mayer: Center for Public Health, Medical University of Vienna
Judit Simon: Center for Public Health, Medical University of Vienna
Maciej Niewada: Medical University of Warsaw
Rok Hren: Institute of Mathematics, Physics, and Mechanics
László Gulácsi: Corvinus University of Budapest

The European Journal of Health Economics, 2019, vol. 20, issue 1, No 15, 155-172

Abstract: Abstract Background To date, a multi-country review evaluating the cost-of-illness (COI) studies from the Central and Eastern European (CEE) region has not yet been published. Our main objective was to provide a general description about published COI studies from CEE. Methods A systematic search was performed between 1 January 2006 and 1 June 2017 in Medline, EMBASE, The Cochrane Library, CINAHL, and Web of Science to identify all relevant COI studies from nine CEE countries. COI studies reporting costs without any restrictions by age, co-morbidities, or treatment were included. Methodology, publication standards, and cost results were analysed. Results We identified 58 studies providing 83 country-specific COI results: Austria (n = 9), Bulgaria (n = 16), Croatia (n = 3), the Czech Republic (n = 10), Hungary (n = 24), Poland (n = 11), Romania (n = 3), Slovakia (n = 3), and Slovenia (n = 4). Endocrine, nutritional, and metabolic diseases (18%), neoplasms (12%), infections (11%), and neurological disorders (11%) were the most frequently studied clinical areas, and multiple sclerosis was the most commonly studied disease. Overall, 57 (98%) of the studies explicitly stated the source of resource use data, 45 (78%) the study perspective, 34 (64%) the costing method, and 24 (58%) reported at least one unit costs. Regardless of methodological differences, a positive relationship was observed between costs of diseases and countries’ per capita GDP. Conclusions Cost-of-illness studies varied considerably in terms of methodology, publication practice, and clinical areas. Due to these heterogeneities, transferability of the COI results is limited across Central and Eastern European countries.

Keywords: Cost-of-illness; Disease burden; Central and Eastern Europe; Austria; Bulgaria; The Czech Republic; Croatia; Hungary; Poland; Romania; Slovakia; Slovenia (search for similar items in EconPapers)
JEL-codes: I10 (search for similar items in EconPapers)
Date: 2019
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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DOI: 10.1007/s10198-019-01066-x

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