A comparison of European, Polish, Slovenian and British EQ-5D-3L value sets using a Hungarian sample of 18 chronic diseases

Zsombor Zrubka (), Zsuzsanna Beretzky, Zoltan Hermann, Valentin Brodszky, László Gulácsi, Fanni Rencz, Petra Baji, Dominik Golicki, Valentina Prevolnik-Rupel and Márta Péntek
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Zsombor Zrubka: Corvinus University of Budapest
Zsuzsanna Beretzky: Corvinus University of Budapest
László Gulácsi: Corvinus University of Budapest
Fanni Rencz: Corvinus University of Budapest
Dominik Golicki: Medical University of Warsaw
Valentina Prevolnik-Rupel: Institute for Economic Research
Márta Péntek: Corvinus University of Budapest

The European Journal of Health Economics, 2019, vol. 20, issue 1, No 12, 119-132

Abstract: Abstract Background In the Central and Eastern European region, the British EQ-5D-3L value set is used commonly in quality of life (QoL) studies. Only Poland and Slovenia have country-specific weights. Our study aimed to investigate the impact of value set choice on the evaluation of 18 chronic conditions in Hungary. Methods Patients’ EQ-5D-3L index scores were calculated using the VAS-based Slovenian and European and the time-trade-off-based Polish and British value sets. We performed pairwise comparisons of mean index values by dimensions, diagnoses and age groups. We evaluated disease burden by comparing index values matched by age and gender in each condition with those of the general population of the CEE region in all four value sets. Results Altogether, 2421 patients (55% female) were included in our sample with the average age of 55.87 years (SD = 17.75). The average Slovenian, European, Polish and British EQ-5D-3L scores were 0.598 (SD = 0.279), 0.661 (SD = 0.257), 0.770 (SD = 0.261) and 0.644 (SD = 0.279), respectively. We found highly significant differences in most diagnoses, with the greatest difference between the Polish and Slovenian index values in Parkinson’s disease (0.265). Systematic pairwise comparison across all conditions and value sets revealed greatest differences between the time-trade-off (TTO) and VAS-based value sets as well as varying sensitivity of the disease burden evaluations of chronic disease conditions to the choice of value sets. Conclusions Our results suggest that the choice of value set largely influences the health state utility results in chronic diseases, and might have a significant impact on health policy decisions.

Keywords: EQ-5D-3L; Value set; Chronic disease; Quality of life; Disease burden; Hungary; Slovenia; Poland (search for similar items in EconPapers)
JEL-codes: I10 (search for similar items in EconPapers)
Date: 2019
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Citations: View citations in EconPapers (1)

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DOI: 10.1007/s10198-019-01069-8

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