The role of income disparities on survival in metastatic clear cell renal cell carcinoma in the targeted therapy era

Yawen Zheng, Yilun Sun, Hongyan Yang, Jie Liu, Ligang Xing () and Yuping Sun ()
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Yawen Zheng: Shandong University, Shandong First Medical University
Yilun Sun: University of Michigan
Hongyan Yang: Shandong University, Shandong First Medical University
Jie Liu: Shandong University, Shandong First Medical University
Ligang Xing: Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Yuping Sun: Shandong University, Shandong First Medical University

The European Journal of Health Economics, 2020, vol. 21, issue 8, No 9, 1223-1233

Abstract: Abstract Purpose The influence of socioeconomic status on metastatic clear cell renal cell carcinoma (RCC) in the target therapy era is still unknown. This study aimed to assess the role of income disparities on prognosis of mRCC in the targeted therapy era. Patients and methods Data of patients with mRCC were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Median household income (MHI) was used to represent patients’ socioeconomic status, and its role on overall survival (OS) and cancer-specific survival (CSS) was evaluated. Results A total of 3791 patients with clear cell mRCC diagnosed between 2010 and 2015 were enrolled in cohort one. There was an obvious imbalance of race and insurance status in patients with difference MHI. Compared with patients in the poorest quartile 1 (Q1), those in the wealthiest Q4 had a 4-month prolonged OS (P

Keywords: Metastatic clear cell renal cell carcinoma; Income disparities; Survival gaps; Targeted therapy era (search for similar items in EconPapers)
Date: 2020
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DOI: 10.1007/s10198-020-01223-7

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