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A dynamic Markov model to assess the cost-effectiveness of the Kidney Team at Home intervention in The Netherlands

Steef Redeker (), Sohal Ismail, Hester V. Eeren, Emma K. Massey, Willem Weimar, Mark Oppe and Jan Busschbach
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Steef Redeker: Erasmus Medical Center, Section of Medical Psychology and Psychotherapy, Department of Psychiatry, Postal Address
Sohal Ismail: Erasmus Medical Center, Section of Medical Psychology and Psychotherapy, Department of Psychiatry, Postal Address
Hester V. Eeren: Erasmus Medical Center, Section of Medical Psychology and Psychotherapy, Department of Psychiatry, Postal Address
Emma K. Massey: Erasmus MC, Transplant Institute, Department of Internal Medicine
Willem Weimar: Erasmus MC, Transplant Institute, Department of Internal Medicine
Mark Oppe: Maths in Health
Jan Busschbach: Erasmus Medical Center, Section of Medical Psychology and Psychotherapy, Department of Psychiatry, Postal Address

The European Journal of Health Economics, 2022, vol. 23, issue 4, No 3, 597-606

Abstract: Abstract Objectives The Kidney Team at Home program is an educational intervention aimed at patients with chronic kidney disease to assist them in their choice for kidney replacement therapy. Previous studies have shown that the intervention results in an increase in knowledge and communication on kidney replacement therapy, and eventually in an increase in the number of living donor kidney transplantations. The study assesses the cost-effectiveness of the intervention compared to standard care. Methods A dynamic probabilistic Markov model was used to estimate the monetary and health benefits of the intervention in The Netherlands over 10 years. Data on costs and health-related quality of life were derived from the literature. Transition probabilities, prevalence, and incidence rates were calculated using a large national database. An optimistic and a pessimistic implementation scenario were compared to a base case scenario with standard care. Results In both the optimistic and pessimistic scenario, the intervention is cost-effective and dominant compared to standard care: savings were €108,681,985 and €51,770,060 and the benefits were 1382 and 695 QALYs, respectively. Conclusions The superior cost-effectiveness of the intervention is caused by the superior health effects and the reduction of costs associated with transplantation, and the relatively small incremental costs of the intervention. The favorable findings of this implementation project resulted in national uptake of the intervention in The Netherlands as of 2021. This is the first time a psychosocial intervention has been implemented as part of standard care in a kidney replacement therapy program worldwide.

Keywords: Patient education; Cost-effectiveness analysis; Organ donation; Home-based educational program; Markov model (search for similar items in EconPapers)
Date: 2022
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DOI: 10.1007/s10198-021-01383-0

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