Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L descriptive systems and utilities in atopic dermatitis

Kamilla Koszorú, Krisztina Hajdu, Valentin Brodszky, Alex Bató, L. Hunor Gergely, Anikó Kovács, Zsuzsanna Beretzky, Miklós Sárdy, Andrea Szegedi and Fanni Rencz ()
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Kamilla Koszorú: Semmelweis University
Krisztina Hajdu: University of Debrecen
Alex Bató: Semmelweis University
L. Hunor Gergely: Semmelweis University
Anikó Kovács: Semmelweis University
Zsuzsanna Beretzky: Corvinus University of Budapest
Miklós Sárdy: Semmelweis University
Andrea Szegedi: University of Debrecen
Fanni Rencz: Corvinus University of Budapest

The European Journal of Health Economics, 2023, vol. 24, issue 1, No 12, 139-152

Abstract: Abstract Background Atopic dermatitis (AD) is a common chronic inflammatory skin disorder affecting up to 10% of adults. The EQ-5D is the most commonly used generic preference-accompanied measure to generate quality-adjusted life years (QALYs) for economic evaluations. Objectives We aimed to compare psychometric properties of the three-level and five-level EQ-5D (EQ-5D-3L and EQ-5D-5L) in adult patients with AD. Methods In a multicentre cross-sectional study, 218 AD patients with a broad range of severity completed the EQ-5D-3L, EQ-5D-5L, Dermatology Life Quality Index (DLQI) and Skindex-16. Disease severity outcomes included the Investigator Global Assessment, Eczema Area and Severity Index and the objective SCORing Atopic Dermatitis. Results A good agreement was established between the two EQ-5D versions with an intraclass correlation coefficient of 0.815 (95% CI 0.758–0.859, p

Keywords: EQ-5D-3L; EQ-5D-5L; Atopic dermatitis; Psychometrics; Utility (search for similar items in EconPapers)
JEL-codes: I10 (search for similar items in EconPapers)
Date: 2023
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Citations: View citations in EconPapers (2)

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DOI: 10.1007/s10198-022-01460-y

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