Comparison of EQ-5D-5L and EORTC QLU-C10D utilities in gastric cancer patients

Chen-Wei Pan, Jun-Yi He, Yan-Bo Zhu, Chun-Hua Zhao, Nan Luo and Pei Wang ()
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Chen-Wei Pan: Medical College of Soochow University
Jun-Yi He: Fudan University
Yan-Bo Zhu: The First Affiliated Hospital of Soochow University
Chun-Hua Zhao: The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalNanjing Medical University
Nan Luo: National University of Singapore
Pei Wang: Fudan University

The European Journal of Health Economics, 2023, vol. 24, issue 6, No 4, 885-893

Abstract: Abstract Background To compare measurement properties of the utility scores derived from various country-specific value sets of EQ-5D-5L (5L) and EORTC QLU-C10D (10D) in gastric cancer patient. Methods The study used cross-sectional data of 243 Chinese gastric cancer patients who completed both 5L and EORTC QLQ-C30. Utility score of QLU-C10D is generated from all the available QLU-C10D value sets currently; the score of 5L is derived from the corresponding 5L value sets for the countries with both the 5L and QLU-C10D value sets and the Chinese 5L value set. Convergent validity was evaluated by testing their correlations with the VAS score. Known-group validity was assessed by comparing the utility scores the patients with different severities. Their relative efficiency (RE) was also compared. Results Correlation coefficient of 5L and QLU-C10D utility scores with VAS ranged from 0.54 to 0.59, and 0.55 to 0.63, respectively. Both the utility scores were in general able to discriminate the patients with different severities; and 5L utility score had higher RE in the majority of known-groups. Conclusion EQ-5D-5L and QLU-C10D utility scores were different and, thus, non-swappable. They possess similar convergent validity and known-group validity; while EQ-5D-5L scores may have better discriminative power.

Keywords: EORTC QLU-C10D; EORTC QLQ-C30; EQ-5D; Utility; Measurement properties; I1 (search for similar items in EconPapers)
Date: 2023
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DOI: 10.1007/s10198-022-01523-0

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