The EORTC QLU-C10D: the Hong Kong valuation study

Richard Huan Xu (), Eliza Lai-yi Wong, Nan Luo, Richard Norman, Jens Lehmann, Bernhard Holzner, Madeleine T. King and Georg Kemmler
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Richard Huan Xu: The Hong Kong Polytechnic University
Eliza Lai-yi Wong: The Chinese University of Hong Kong
Nan Luo: The National University of Singapore
Richard Norman: Curtin University
Jens Lehmann: Medical University of Innsbruck
Bernhard Holzner: Medical University of Innsbruck
Madeleine T. King: University of Sydney
Georg Kemmler: Medical University of Innsbruck

The European Journal of Health Economics, 2024, vol. 25, issue 5, No 11, 889-901

Abstract: Abstract Objective The EORTC QLU-C10D is a new preference-based measure derived from the EORTC QLQ-C30. Country-specific value sets are required to support the cost-utility analysis of cancer-related interventions. This study aimed to generate an EORTC QLU-C10 value set for Hong Kong (HK). Methods A HK online panel was quota-sampled to achieve an adult general population sample representative by sex and age. Participants were invited to complete an online discrete choice experiment survey. Each participant was asked to complete 16 choice-pairs, randomly assigned from a total of 960 choice-pairs, each comprising two QLU-C10D health states and a duration attribute. Conditional and mixed logistic regression analyses were used to analyse the data. Results The analysis included data from 1041 respondents who had successfully completed the online survey. The distribution of sex did not differ from that of the general population, but a significant difference was found among age groups. A weighting analysis for non-representative variable (age) was used. Utility decrements were generally monotonic, with the largest decrements for physical functioning (− 0.308), role functioning (− 0.165), and pain (− 0.161). The mean QLU-C10D utility score of the participants was 0.804 (median = 0.838, worst to best = − 0.169 to 1). The value of the worst health state was − 0.223, which was sufficiently lower than 0 (being dead). Conclusions This study established HK utility weights for the QLU-C10D, which can facilitate cost-utility analyses across cancer-related health programmes and technologies.

Keywords: Utility weights; Discrete choice experiment; EORTC QLQ-C30; QLU-C10D; Hong Kong; Quality of life; Decision making (search for similar items in EconPapers)
JEL-codes: I15 (search for similar items in EconPapers)
Date: 2024
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DOI: 10.1007/s10198-023-01632-4

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