Association between chronic pain and dementia: a systematic review and meta-analysis

Zhenzhi Wang (), Zhen Sun and Hui Zheng ()
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Zhenzhi Wang: Chengdu University of Traditional Chinese Medicine
Zhen Sun: Shanghai Jiao Tong University School of Medicine
Hui Zheng: Chengdu University of Traditional Chinese Medicine

European Journal of Ageing, 2024, vol. 21, issue 1, No 17, 26 pages

Abstract: Abstract Purpose Dementia and chronic pain (CP) are prevalent among older adults. However, no study has systematically reviewed the association between dementia and CP. Therefore, we performed this study to gather evidence about the potential relationship between the two. Methods Two authors independently searched PubMed, Embase, and Web of Science to identify all records published up to 1 September 2022 that explored the association between CP and dementia. The methodological quality of the studies was assessed using the Newcastle Ottawa Scale (NOS). A fixed or random-effects model was used to pool the risk estimates. Results Among the initial 3296 articles retrieved, 19 were included in the review (1 cross-sectional, and 18 cohort). The pooled result showed the risk of dementia was 1.42 times higher in CP patients (HR = 1.42, 95% CI 1.23–1.64, P

Keywords: Chronic pain; Dementia; Meta-analysis; Systematic review (search for similar items in EconPapers)
Date: 2024
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DOI: 10.1007/s10433-024-00812-2

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