BRAIN-Diabetes: a randomised trial to test the feasibility of an adapted FINGER multidomain intervention in adults with type 2 diabetes living in rural border regions of Ireland

Claire T. McEvoy (), Geraldine McCarthy, Rebecca F. Townsend, Catherine Dolan, Joanne Regan-Moriarty, Christopher Cardwell, Bernadette McGuinness, Seán P. Kennelly, Jim Kelly, Catherine McHugh, Frank Kee, John Bartlett, Caroline Bradshaw, Orla Reynolds, Valerie Mortland, Christina O’Neill, Ingrid McLoughlin, Noel McCaffrey, Margaret Heffernan, Cabrini Nolan and Peter A. Passmore
Additional contact information
Claire T. McEvoy: Queen’s University Belfast
Geraldine McCarthy: National University of Ireland, Galway and Sligo Leitrim Mental Health Services
Rebecca F. Townsend: Newcastle University
Catherine Dolan: National University of Ireland, Galway and Sligo Leitrim Mental Health Services
Joanne Regan-Moriarty: Atlantic Technological University
Christopher Cardwell: Queen’s University Belfast
Bernadette McGuinness: Queen’s University Belfast
Seán P. Kennelly: Tallaght University Hospital
Jim Kelly: South West Acute Hospital, Western Health and Social Care Trust
Catherine McHugh: Sligo University Hospital
Frank Kee: Queen’s University Belfast
John Bartlett: Atlantic Technological University
Caroline Bradshaw: National University of Ireland, Galway and Sligo Leitrim Mental Health Services
Orla Reynolds: National University of Ireland, Galway and Sligo Leitrim Mental Health Services
Valerie Mortland: South West Acute Hospital, Western Health and Social Care Trust
Christina O’Neill: Queen’s University Belfast
Ingrid McLoughlin: Atlantic Technological University
Noel McCaffrey: ExWell Medical, Irish Wheelchair Association
Margaret Heffernan: National University of Ireland, Galway and Sligo Leitrim Mental Health Services
Cabrini Nolan: Sligo University Hospital
Peter A. Passmore: Queen’s University Belfast

European Journal of Ageing, 2025, vol. 22, issue 1, No 30, 12 pages

Abstract: Abstract Background The Border Region Area lifestyle INtervention for healthy cognitive ageing in Diabetes’ (BRAIN-Diabetes) trial aimed to test the feasibility of an adapted version of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multidomain intervention in cognitively healthy adults at risk of dementia living in border regions of Ireland. Methods BRAIN-Diabetes was a 6-month randomised controlled pilot trial involving adults living in rural border regions who were ≥ 50 years old, without existing dementia but had a diagnosis of type 2 diabetes and access to a computer. Individuals were randomised to either the multidomain intervention or the standard care control group. The intervention included diet counselling, physical exercise and computerised cognitive training which were delivered remotely and cardiometabolic risk monitoring which was delivered in person. The primary outcomes assessed feasibility of recruitment/retention and adherence to the intervention. Other outcomes explored intervention effects on cognitive, metabolic and health-related quality of life. Results In total, 156 individuals were assessed for eligibility, and 79 (51%) were recruited (mean age 61.6 ± 6.9 (range 60–75) years; 68% male). After 6 months, retention was 81% (72% in intervention versus 90% control). Adherence rate was high with most participants attending > 50% of the scheduled intervention sessions. There was greater improvement in diet quality (p

Keywords: Multidomain intervention; Feasibility; Cognitive performance (search for similar items in EconPapers)
Date: 2025
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DOI: 10.1007/s10433-025-00862-0

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