Innovative and conventional “conservative” technologies for the treatment of uterine fibroids in Italy: a multidimensional assessment

L. Ferrario (), E. Garagiola, C. Gerardi, G. Bellavia, S. Colombo, C. Ticca, C. Rossetti, M. Ciboldi, M. Meroni, A. Vanzulli, A. Rampoldi, T. Bignardi, F. Arrigoni, E. Porazzi and E. Foglia
Additional contact information
L. Ferrario: LIUC- Università Cattaneo
E. Garagiola: LIUC- Università Cattaneo
C. Gerardi: IRCCS- Istituto di Ricerche Farmacologiche “Mario Negri”
G. Bellavia: ASST Grande Ospedale Metropolitano Niguarda
S. Colombo: ASST Grande Ospedale Metropolitano Niguarda
C. Ticca: ASST Grande Ospedale Metropolitano Niguarda
C. Rossetti: ASST Grande Ospedale Metropolitano Niguarda
M. Ciboldi: ASST Grande Ospedale Metropolitano Niguarda
M. Meroni: ASST Grande Ospedale Metropolitano Niguarda
A. Vanzulli: ASST Grande Ospedale Metropolitano Niguarda
A. Rampoldi: ASST Grande Ospedale Metropolitano Niguarda
T. Bignardi: ASST Grande Ospedale Metropolitano Niguarda
F. Arrigoni: University of L’Aquila
E. Porazzi: LIUC- Università Cattaneo
E. Foglia: LIUC- Università Cattaneo

Health Economics Review, 2022, vol. 12, issue 1, 1-10

Abstract: Abstract Background To evaluate the potential benefits of the Magnetic Resonance-guided high intensity Focused Ultrasound (MRgFUS) introduction in the clinical practice, for the treatment of uterine fibroids, in comparison with the standard “conservative” procedures, devoted to women who wish to preserve their uterus or enhance fertility: myomectomy and uterine artery embolization (UAE). Methods A Health Technology Assessment was conducted, assuming the payer’s perspective (Italian National Healthcare Service). The nine EUnetHTA Core Model dimensions were deeply investigated, by means of i) a literature review; ii) the implementation of health economics tools (useful for uterine fibroids patients’ clinical pathway economic evaluation, and budget impact analysis), to define MRgFUS economic and organizational sustainability, and iii) administration of specific questionnaires filled by uterine fibroids’ experts, to gather their perceptions on the three possible conservative approaches (MRgFUS, UAE and myomectomy). Results Literature revealed that MRgFUS would generate several benefits, from a safety and an efficacy profile, with significant improvement in symptoms relief. Advantages emerged concerning the patients’ perspective, thus leading to a decrease both in the length of hospital stay (p-value

Keywords: Economic evaluation; Technology assessment; Magnetic resonance imaging/methods; Ultrasound therapy/methods; Decision support techniques (search for similar items in EconPapers)
Date: 2022
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DOI: 10.1186/s13561-022-00367-x

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