Passive smoking and chronic obstructive pulmonary disease mortality: findings from the Japan collaborative cohort study

Shigekazu Ukawa, Akiko Tamakoshi (), Hiroshi Yatsuya, Kazumasa Yamagishi, Masahiko Ando and Hiroyasu Iso
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Shigekazu Ukawa: Hokkaido University Graduate School of Medicine
Akiko Tamakoshi: Hokkaido University Graduate School of Medicine
Hiroshi Yatsuya: Fujita Health University
Kazumasa Yamagishi: University of Tsukuba
Masahiko Ando: Nagoya University Hospital
Hiroyasu Iso: Osaka University Graduate School of Medicine

International Journal of Public Health, 2017, vol. 62, issue 4, No 7, 489-494

Abstract: Abstract Objectives To elucidate the association between passive smoking at home and chronic obstructive pulmonary disease (COPD) mortality via a large-scale nationwide cohort study in Japan. Methods Never smokers (n = 34,604) aged 40–79 years at baseline (1988–1990; 4884 men, 29,720 women) were included in the analysis. Passive smoking at home was measured based on self-reported frequency of weekly exposure to passive smoking at home. An inverse probability of treatment-weighted competing risk model was used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for COPD mortality. Results During a median follow-up of 16.4 years, 33 participants (10 men, 23 women) died of COPD. The HR for participants exposed to passive smoking at home ≤4 days per week or those who had almost daily exposure to passive smoking at home had a significantly increased risk of COPD mortality (HR 2.40, 95% CI 1.39–4.15, HR 2.88, 95% CI 1.68–4.93, respectively). Conclusions The present findings suggest that avoiding passive smoking at home may be beneficial for preventing death due to COPD among never smokers.

Keywords: Smoking; Passive; Chronic obstructive pulmonary disease; Mortality; Cohort study (search for similar items in EconPapers)
Date: 2017
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DOI: 10.1007/s00038-016-0938-1

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