Which clinical and neuropsychological factors are responsible for cognitive impairment in patients with epilepsy?

Dominika Jarčušková (), Miroslava Palušná (), Jakub Gazda (), Eva Feketeová () and Zuzana Gdovinová ()
Additional contact information
Dominika Jarčušková: P. J. Safarik University
Miroslava Palušná: P. J. Safarik University
Jakub Gazda: University Hospital of L. Pasteur Kosice
Eva Feketeová: P. J. Safarik University
Zuzana Gdovinová: P. J. Safarik University

International Journal of Public Health, No 0, 10 pages

Abstract: Abstract Objectives The study aimed to assess the effect of demographic and clinical features of epilepsy, anxiety, depressed mood, sleep, and quality of life on the prediction of cognitive decline in patients with epilepsy. Methods Two hundred and six consecutive patients with epilepsy (age 41.8 ± 15.6 years, mean, SD) out of 279, were included in this cross-sectional study. We used simple linear regression to calculate the results. Results Objective cognitive status was predicted by anxiety and depression mood changes (Beck Anxiety Inventory (BAI), p = 0.03, Beck Depression Inventory (BDI), p = 0.005), language subdomain of Quality of Life Inventory in Epilepsy-89 (QOLIE-89) (p = 0.003), and total QOLIE-89 (p = 0.001). No significance was shown in demographic and clinical features of epilepsy (gender, age at onset, epilepsy duration, type, etiology of epilepsy, and antiepileptic treatment), except frequency of generalized epileptic seizures (p = 0.03), which also served as an independent predictor of anxiety (BAI) and depression (BDI). Conclusions Our findings point at the role of mood changes in the cognitive status of patients with epilepsy, which should be used as an essential therapeutic target apart of seizure control.

Keywords: Cognition; Epilepsy; EpiTrack; Cognitive impairment; Depression; Anxiety (search for similar items in EconPapers)
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://link.springer.com/10.1007/s00038-020-01401-7 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:spr:ijphth:v::y::i::d:10.1007_s00038-020-01401-7

Ordering information: This journal article can be ordered from
http://www.springer.com/economics/journal/00038

DOI: 10.1007/s00038-020-01401-7

Access Statistics for this article

International Journal of Public Health is currently edited by Thomas Kohlmann, Nino Künzli and Andrea Madarasova Geckova

More articles in International Journal of Public Health from Springer, Swiss School of Public Health (SSPH+)
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().