A new approach to regression analysis of censored competing-risks data
Yuxue Jin () and
Tze Leung Lai ()
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Yuxue Jin: Quantitative Marketing, Google
Tze Leung Lai: Stanford University
Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, 2017, vol. 23, issue 4, No 5, 605-625
Abstract:
Abstract An approximate likelihood approach is developed for regression analysis of censored competing-risks data. This approach models directly the cumulative incidence function, instead of the cause-specific hazard function, in terms of explanatory covariates under a proportional subdistribution hazards assumption. It uses a self-consistent iterative procedure to maximize an approximate semiparametric likelihood function, leading to an asymptotically normal and efficient estimator of the vector of regression parameters. Simulation studies demonstrate its advantages over previous methods.
Keywords: Asymptotic efficiency; Cumulative incidence function; Empirical process theory; Hazard function of subdistribution; Martingale central limit theorem; Semiparametric likelihood; Volterra equation (search for similar items in EconPapers)
Date: 2017
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DOI: 10.1007/s10985-016-9378-8
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