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PharmacoEconomics

1997 - 2026

Current editor(s): Timothy Wrightson and Christopher I. Carswell

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Volume 44, issue 5, 2026

Subgroup Modelling and Use of External Evidence in Precision Oncology Appraisals: An External Assessment Group Perspective on the NICE Single Technology Appraisal of Zolbetuximab for Untreated CLDN18.2-Positive HER2-Negative Unresectable Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma pp. 509-513 Downloads
Mirre Scholte, Andrea Fernández Coves, Huiqin Yang, Nigel Armstrong, Kevin McDermott, Xiaoyu Tian, Lisa Stirk, Robert Wolff, Manuela A. Joore and Sabine E. Grimm
The Value of Combination Vaccines in Children and Adults: More than the Sum of Their Parts pp. 515-516 Downloads
Anthony T. Newall
Estimating the Value of Combination Vaccines: A Methodological Framework pp. 517-526 Downloads
Mark Jit, Allison Portnoy, Clint Pecenka, William P. Hausdorff and Christopher Gill
Patient-Level Health Economic Modeling in Excel Without VBA: A Tutorial pp. 527-538 Downloads
Rob Blissett, Will Sullivan, Inola Subban and Adam Igloi-Nagy
A Modern Approach for Constructing Decision Analytic Models in Microsoft Excel pp. 539-558 Downloads
Mike Paulden
A Systematic Review of the Economic Burden of Prostate Cancer: Direct and Indirect Cost Perspectives pp. 559-583 Downloads
Josep Darbà, Meritxell Ascanio and Antonio Rodríguez
Innovative Contracting for Gene Therapies: Current Landscape and Perspectives on the Future of Gene Therapy Financing in the USA pp. 585-598 Downloads
Tyler D. Wagner, Jacqlyn W. Riposo, Kendra M. Gould, Jonathan D. Campbell, James T. Kenney, Claire M. Csenge and Theresa Schmidt
Are Health Gains to Children and Adolescents More Important Than Health Gains to Adults? A Person Trade-Off Study pp. 599-613 Downloads
Tessa Peasgood, Udeni De Silva Perera, Gang Chen, Cate Bailey, Richard Norman, Rosalie Viney, Koonal Shah and Nancy Devlin
The Cost Effectiveness of Upgrading Cochlear Implant Sound Processors in Australia: A Novel Application of Individual-Level Microsimulation Models pp. 615-638 Downloads
Bonny Parkinson, Elizabeth Seil, Rajan Sharma, Paola Incerti, Jason Gavrilis, Antonio Ahumada-Canale and Padraig Kitterick
Comment on “The Importance of Structured Expert Elicitation to Inform Outcomes Following Treatment Discontinuation: Evidence Assessment Group Perspective” pp. 639-640 Downloads
Dyfrig A. Hughes
Response to Comment on “The Importance of Structured Expert Elicitation to Inform Outcomes Following Treatment Discontinuation: Evidence Assessment Group Perspective” pp. 641-642 Downloads
Hangjian Wu, Cristina Fernandez-Garcia and Stephen Rice
Correction: Estimating the Value of Combination Vaccines: A Methodological Framework pp. 643-646 Downloads
Mark Jit, Allison Portnoy, Clint Pecenka, William P. Hausdorff and Christopher Gill

Volume 44, issue 4, 2026

Lowering the Barriers to the Appropriate Use of Individual-Level Simulation for Health Economic Evaluation pp. 375-377 Downloads
Salah Ghabri, Jonathan Karnon and J. Jaime Caro
Microsimulation Modeling for Health Decision Sciences Using C++: A Tutorial pp. 379-387 Downloads
Aku-Ville Lehtimäki and Janne Martikainen
Beyond the States: Developing a Discrete Event Simulation Model Using R pp. 389-408 Downloads
Ziyi Lin and Andrew Briggs
Discrete-Event Simulation Modeling Framework for Cancer Interventions and Population Health in R (DESCIPHR): An Open-Source Pipeline pp. 409-427 Downloads
Selina Pi, Carolyn M. Rutter, Carlos Pineda-Antunez, Jonathan H. Chen, Jeremy D. Goldhaber-Fiebert and Fernando Alarid-Escudero
Comparing the Influence of Heterogeneity on Model Outcomes in Individual-Level and Cohort Simulations: An Exploratory Simulation Study pp. 429-437 Downloads
Evelien B. van Well, Tim M. Govers and Hendrik Koffijberg
Individualized Treatment Rules Based on Cost-Effectiveness Criteria in Microsimulations pp. 439-450 Downloads
Niklaus Meier, Ana Cecilia Quiroga Gutierrez, Mark Pletscher and Matthias Schwenkglenks
Deriving an Analytical Solution to Inversion of Royston/Parmar Restricted Cubic Spline Parametric Survival Models for Discrete Event Simulation pp. 451-459 Downloads
George Bungey, Jorgen Moller, James Saunders and Venediktos Kapetanakis
Developing and Calibrating a Colorectal Cancer Microsimulation Model for Northern Ireland pp. 461-475 Downloads
Olivia Adair, Ethna McFerran, Mark Lawler, Luuk A. van Duuren and Felicity Lamrock
Spectrum of Models for Assessing the Cost Effectiveness of Total Knee Replacement Implants: A Comparison of Discrete-Time Cohort Markov and Continuous-Time Individual-Level Multistate Models pp. 477-494 Downloads
Yixin Xu, Elsa M. R. Marques, Nicky J. Welton, Linda P. Hunt, Michael Whitehouse, Ashley W. Blom, Andrew D. Beswick and Howard H. Z. Thom
Development of a Patient-Level Multi-objective Optimisation Model for Screening Strategies for Childhood Type 1 Diabetes pp. 495-507 Downloads
Gonçalo Leiria, R. Brett McQueen, Conner Jackson, Marian Rewers, William A. Hagopian, Richard A. Oram, Jonathan E. Fieldsend and Lauric A. Ferrat

Volume 44, issue 3, 2026

The Importance of Structured Expert Elicitation to Inform Outcomes Following Treatment Discontinuation: Evidence Assessment Group Perspective pp. 263-266 Downloads
Hangjian Wu, Cristina Fernandez-Garcia, Nicole O’Connor, Oleta Williams, Sola Akinbolade, Ayomikun Ogunyemi, Sonia Garcia Gonzalez-Moral, Fiona Beyer, Nick Meader and Stephen Rice
EQ-5D(-Y) Valuation from Adult and Child Perspectives: Where Does the Empirical Evidence Leave Us and How Should We Proceed? pp. 267-278 Downloads
Stefan A. Lipman and Zhirui Guo
Practical Considerations for Incorporating Equity More Explicitly in Australian Health Technology Assessment Processes pp. 279-286 Downloads
Anagha Killedar, Martin Howell, Kirsten Howard and Sarah Norris
Comparative Economic Evaluations of CAR-T Therapies for Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Systematic Review pp. 287-298 Downloads
Tien Hoang Tran and Hyung Seok John Kim
Economic Evaluations of Medication Safety Interventions in Primary and Long-Term Care: A Systematic Review pp. 299-316 Downloads
Sneha T. Amritlal, Rosalyn Chandler, Alireza Mahboub-Ahari, Luke Paterson, Anthony J. Avery, Darren M. Ashcroft, Antony Chuter and Rachel A. Elliott
A Method for Comparing Health Inequality Impact Magnitudes, with an Illustration for Hypothetical Treatments of 1336 Diseases pp. 317-328 Downloads
Richard Cookson, Gunjeet Kaur, Ieva Skarda, Shrathinth Venkatesh, Tim Doran, Ole F. Norheim, Mike Paulden and Owen O’Donnell
Development of Cardiovascular Risk Equations in People with Overweight or Obesity and Established Cardiovascular Disease Without Diabetes Based on the SELECT Trial pp. 329-341 Downloads
Martin Bøg, Anders Bo Bojesen, Scott Emerson, Milana Ivkovic, Nia C. Jenkins, Christopher Lübker, Muhammad Mamdani, Thomas Padgett, Luc Van Gaal, Peter E. Weeke and A. Michael Lincoff
Public Health Impact and Cost-Effectiveness of Routine and Catch-Up Human Papillomavirus Vaccination in Girls and Women in Selected Regions of China: A Model-Based Study pp. 343-357 Downloads
Xiaoya Fu, Qian Zhang, Abram L. Wagner, Ye Yao, Yilan Xia, Fengge Wang and Yihan Lu
Bevacizumab for Metastatic Colorectal Cancer with Chromosomal Instability: Cost-Effectiveness Analysis for a Novel Precision Treatment Approach in Germany, Ireland and Spain pp. 359-374 Downloads
Jonathan Briody, Ian S. Miller, James F. O’Mahony, Lesley Tilson, Alice C. O’Farrell, Qiushi Chen, Verena Murphy, Orla Casey, Nadine Schulte, Matthias P. Ebert, Jochen H. M. Prehn, Diether Lambrechts, Bauke Ylstra, Rodrigo Dienstmann, Annette T. Byrne and Kathleen Bennett

Volume 44, issue 2, 2026

Re-anchoring the Value of Innovative Therapies in NICE Decision Making When Comparators are Cost Ineffective: A Case Study of Late-Onset Pompe Disease pp. 105-113 Downloads
Matthew Walton, Nyanar J. Deng, Mark Corbett, Chinyereugo Umemneku-Chikere, Sarah J. Nevitt, Helen Fulbright, Chong Yew Tan, Robin Lachmann, Rachel Churchill and Robert Hodgson
The ‘Values in Modelling’ Framework for Patient and Public Involvement in Health Economics Modelling: Development and Application in the LEAP Model Project pp. 115-139 Downloads
Stephanie Harvard, Rachel Carter, Sian Hoe Cheong, Tony Lanier, Zainab Zeyan, Amin Adibi, Spencer Lee, Cristina Novacovik, Mark Ewert, Eric B. Winsberg and Kate M. Johnson
Improving Collaborative Engagement in Health State Valuation: A Scoping Review of Current Practices and Emerging Recommendations pp. 141-163 Downloads
Philip A. Powell, Victoria Gale, Gurdas Singh, Anthea Sutton, Janine Verstraete, Nancy Devlin, Michael Herdman, Simone Schieskow and Jill Carlton
A Systematic Review of Decision-Analytic Modelling Approaches in Economic Evaluations of Post-traumatic Stress Disorder Treatments pp. 165-185 Downloads
Sheradyn R. Matthews, Laura C. Edney and Reginald D. V. Nixon
Mapping Health State Utility from Disease-Specific Measures in Spinal Muscular Atrophy and Paroxysmal Nocturnal Hemoglobinuria pp. 187-205 Downloads
Ziwen Zhao, Zhao Shi, Lei Dou, Chaofan Li and Shunping Li
Cost Effectiveness of Efanesoctocog Alfa Versus Factor VIII Extended Half-Life in Adolescent and Adult Patients with Hemophilia A in the USA pp. 207-218 Downloads
Amy Dymond, Alix Arnaud, Ion Agirrezabal and Will Green
External Validation of the MicroSimulation Core Obesity Model (MS-COM) to Predict Cardiovascular Outcomes, Mortality and Type 2 Diabetes Mellitus Incidence and Assess Cost Effectiveness pp. 219-231 Downloads
Christopher G. Fawsitt, Howard Thom, David Aceituno, Alexander Jarde, Sara Larsen, Christopher Lübker, Edward Kayongo, Edna Keeney and Volker Foos
Health-Service Costs for the Treatment of Multidrug-Resistant/Rifampicin-Resistant Tuberculosis in South African Children: Application of a Real-World Dataset pp. 233-244 Downloads
Thomas Wilkinson, Arne von Delft, Anneke C. Hesseling, Edina Sinanovic, H. Simon Schaaf and James A. Seddon
Model-Based Economic Evaluation of the First-in-Class Myosin Inhibitor Mavacamten Versus Care as Usual in Obstructive Hypertrophic Cardiomyopathy Patients from a Dutch Societal Perspective pp. 245-259 Downloads
Isabell Wiethoff, Willem J. A. Witlox, Silvia M. A. A. Evers, Michelle Michels and Mickaël Hiligsmann
Correction: Cost Effectiveness of Exclusionary EGFR Testing for Taiwanese Patients Newly Diagnosed with Advanced Lung Adenocarcinoma pp. 261-261 Downloads
Huang-Tz Ou, Jui-Hung Tsai, Yi-Lin Chen, Tzu-I. Wu, Li-Jun Chen and Szu-Chun Yang

Volume 44, issue 1, 2026

Economic Consequences of Increasing the NICE Cost-Effectiveness Threshold pp. 5-8 Downloads
Mike Paulden
Lollipop Plots to Communicate Cost-Effectiveness Scenario Analyses Results pp. 9-12 Downloads
Isaac Corro Ramos
Caring for and Caring about in Economic Evaluation: Modelling the Family and Caregiving Effects pp. 13-23 Downloads
Becky Pennington, Sarah Davis and Holly Cranmer
Eladocagene Exuparvovec for the Treatment of Aromatic l-Amino Acid Decarboxylase Deficiency (AADCd): An Economic Evaluation from a US Perspective pp. 25-41 Downloads
Rongrong Zhang, Thomas O’Connell, Berrin Monteleone, Yixi Teng, Paul Wuh-Liang Hwu, Paul Castellano and Ioannis Tomazos
Exploring the Generalizability of Foreign Cost-Effectiveness Analysis to Spain Using Data From a Scoping Review of Multinational Studies pp. 43-60 Downloads
Lidia García-Pérez, Ignacio Abásolo-Alessón and Miguel Ángel Negrín-Hernández
The Influence of Perspective on the Valuation of the EQ-5D-Y-3L: A Comparison Using the OPUF Tool and a Discrete Choice Experiment pp. 61-72 Downloads
Jake Hitch, Gayathri Kumar, Paul Schneider, Nancy Devlin, Koonal Shah and David Mott
Cure Models: What is Meant by a Survival ‘Plateau’, and Do Experts Agree on What Constitutes One? pp. 73-82 Downloads
Dan Jackson, Michael Sweeting, Robert Hettle, Binbing Yu, Neil Hawkins, Keith Abrams and Rose Baker
A Post-Market Economic Evaluation of Bortezomib, Lenalidomide and Dexamethasone Versus Pre-funding Standard of Care for Newly Diagnosed Multiple Myeloma Using Registry Data pp. 83-95 Downloads
Adam Irving, Dennis Petrie, Anthony Harris, Laura Fanning, Erica M. Wood, Elizabeth Moore, Cameron Wellard, Neil Waters, Bradley Augustson, Gordon Cook, Francesca Gay, Georgia McCaughan, Peter Mollee, Andrew Spencer and Zoe K. McQuilten
Comment on “Cost Comparisons in NICE Technology Appraisals: An External Assessment Group Perspective” by Marten J. Poley et al pp. 97-98 Downloads
Alexander Allen, Alan Lovell, Ahmed Abdelsabour, Edward C. F. Wilson, G. J. Melendez-Torres and Dawn Lee
Reply to Comment on “Cost Comparisons in NICE Technology Appraisals: An External Assessment Group Perspective” pp. 99-100 Downloads
Marten J. Poley, Nigel Armstrong, Huiqin Yang, Mubarak Patel, Lisa Stirk, Maiwenn J. Al and Isaac Corro Ramos
Correction: How do Health State Values Differ When Respondents Consider Adults Versus Children Living in Those States? A Systematic Review pp. 101-103 Downloads
Ashwini De Silva, Alexander van Heusden, Zhongyu Lang, Nancy Devlin, Richard Norman, Kim Dalziel, Tessa Peasgood and Tianxin Pan
Page updated 2026-05-08