Oral Antiplatelet Therapy in Secondary Prevention of Cardiovascular Events

Bart Heeg (), Joep Damen and Ben Hout

PharmacoEconomics, 2007, vol. 25, issue 12, 1063-1082

Abstract: The cost-effectiveness estimates presented in this article support the NICE guidelines for the use of antiplatelets for the prevention of cardiovascular events. Based on these pharmacoeconomic data alone, aspirin should be prescribed for primary or secondary prevention among patients at high risk of cardiovascular events, dipyridamole for the secondary prevention of stroke (for a maximum of 5 years), and clopidogrel for the treatment of symptomatic cardiovascular disease or acute coronary syndrome (for a maximum of 2 years). The cost effectiveness of antiplatelets hinges on the patient’s initial risk, the risk reduction associated with treatment, and the price of the treatment. Evidence suggests that the cost effectiveness of antiplatelets can be optimized by individualising the treatment decision based on patient risk and expected risk reduction. Copyright Adis Data Information BV 2007

Date: 2007
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DOI: 10.2165/00019053-200725120-00007

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