Evaluating Disease-Modifying Agents: A Simulation Framework for Alzheimer’s Disease
Shien Guo (),
Denis Getsios,
Nikhil Revankar,
Peng Xu,
Gwilym Thompson,
Joel Bobula,
Loretto Lacey and
Maren Gaudig
PharmacoEconomics, 2014, vol. 32, issue 11, 1129-1139
Abstract:
The updated economic model has good predictive power, but validation against longer-term outcomes is still needed. Our analyses also demonstrate the importance of designing a model with sufficient flexibility such that the model allows for assessment of the impact of key sources of uncertainty on the value of DMAs. Copyright Springer International Publishing Switzerland 2014
Date: 2014
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DOI: 10.1007/s40273-014-0203-5
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