Clinical and Economic Impact of Substituting Dexmedetomidine for Propofol due to a US Drug Shortage: Examination of Coronary Artery Bypass Graft Patients at an Urban Medical Centre

Brandi Thoma (), Julius Li, Cara McDaniel, Cindy Wordell, Nicholas Cavarocchi and Laura Pizzi

PharmacoEconomics, 2014, vol. 32, issue 2, 149-157

Abstract: Findings suggest that use of dexmedetomidine as an alternative to propofol for sedation of CABG patients post-operatively contributes to reduced mechanical ventilation time, ICU LOS and post-operative LOS. Higher drug costs resulting from the propofol shortage were offset by savings in post-operative room and board costs. Additional savings may be possible by preventing medical complications to the extent possible. Copyright Springer International Publishing Switzerland 2014

Date: 2014
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DOI: 10.1007/s40273-013-0116-8

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