German Value Set for the EQ-5D-5L

Kristina Ludwig (), Johann Graf von der Schulenburg and Wolfgang Greiner ()
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Kristina Ludwig: Health Economics and Health Care Management, Bielefeld University
Wolfgang Greiner: Health Economics and Health Care Management, Bielefeld University

PharmacoEconomics, 2018, vol. 36, issue 6, No 4, 663-674

Abstract: Abstract Objectives The objective of this study was to develop a value set for EQ-5D-5L based on the societal preferences of the German population. As the first country to do so, the study design used the improved EQ-5D-5L valuation protocol 2.0 developed by the EuroQol Group, including a feedback module as internal validation and a quality control process that was missing in the first wave of EQ-5D-5L valuation studies. Methods A representative sample of the general German population (n = 1158) was interviewed using a composite time trade-off and a discrete choice experiment under close quality control. Econometric modeling was used to estimate values for all 3125 possible health states described by EQ-5D-5L. The value set was based on a hybrid model including all available information from the composite time trade-off and discrete choice experiment valuations without any exclusions due to data issues. Results The final German value set was constructed from a combination of a conditional logit model for the discrete choice experiment data and a censored at −1 Tobit model for the composite time trade-off data, correcting for heteroskedasticity. The value set had logically consistent parameter estimates (p

Date: 2018
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DOI: 10.1007/s40273-018-0615-8

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