A Value Set for the EQ-5D-Y-3L in the Netherlands

Bram Roudijk (), Ayesha Sajjad, Brigitte Essers, Stefan Lipman, Peep Stalmeier and Aureliano Paolo Finch
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Bram Roudijk: EuroQol Research Foundation
Ayesha Sajjad: Erasmus University Rotterdam
Brigitte Essers: Maastricht University Medical Center
Stefan Lipman: Erasmus University Rotterdam
Peep Stalmeier: Radboud University Medical Center
Aureliano Paolo Finch: EuroQol Research Foundation

PharmacoEconomics, 2022, vol. 40, issue 2, No 9, 193-203

Abstract: Abstract Background and Objective There is increasing interest in preference-accompanied measures of health for paediatric populations. The child-friendly EQ-5D version, EQ-5D-Y-3L, is one such instrument, but the lack of a Dutch value set prevents its use in economic evaluations of healthcare interventions in the Netherlands. This study aims at covering this gap by collecting preferences using a standardised protocol for deriving EQ-5D-Y-3L value sets. Methods Composite time trade-off data were collected using videoconferencing interviews, with each respondent completing ten composite time trade-off tasks. Discrete choice experiment data were collected using an online survey, with respondents each completing 15 paired comparisons. Respondents completed these tasks considering what they prefer for a hypothetical 10-year-old child. Discrete choice experiment data were analysed using a ten-parameter mixed-logit model and anchored to the quality-adjusted life-year scale using the mean observed composite time trade-off values. Results The study collected preferences for 197 respondents using composite time trade-off and for 959 respondents using a discrete choice experiment. The discrete choice experiment sample was representative for the Dutch population in terms of age and sex. The level 3 weight for pain/discomfort was the largest, followed by feeling worried, sad or unhappy, usual activities, mobility and self-care. Health state values ranged between −0.218 and 1. Conclusions This study generated a Dutch value set for the EQ-5D-Y-3L, which can be used for the computation of quality-adjusted life-years for economic evaluations of healthcare interventions in paediatric populations.

Date: 2022
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DOI: 10.1007/s40273-022-01192-0

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