Informal Care Costs According to Age and Proximity to Death to Support Cost-Effectiveness Analyses

Saskia Groot (), Irene Santi, Pieter Bakx, Bram Wouterse and Pieter Baal
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Saskia Groot: Erasmus University Rotterdam
Irene Santi: Erasmus University Rotterdam
Pieter Bakx: Erasmus University Rotterdam
Bram Wouterse: Erasmus University Rotterdam
Pieter Baal: Erasmus University Rotterdam

PharmacoEconomics, 2023, vol. 41, issue 9, No 9, 1137-1149

Abstract: Abstract Background Costs of informal care are ignored in many cost-effectiveness analyses (CEAs) conducted from a societal perspective; however, these costs are relevant for lifesaving interventions targeted at the older population. In this study, we estimated informal care costs by age and proximity to death across European regions and showed how these estimates can be included in CEAs. Methods We estimated informal care costs by age and proximity to death using generalised linear mixed-effects models. For this, we selected deceased singles from the Survey of Health, Ageing and Retirement, which we grouped by four European regions. We combined the estimates of informal care costs with life tables to illustrate the impact of including informal care costs on the incremental cost-effectiveness ratio (ICER) of a hypothetical intervention that prevents a death at different ages. Results Informal care use, and hence informal care costs, increase when approaching death and with increasing age. The impact of including informal care costs on the ICER varies between €200 and €17,700 per quality-adjusted life-year gained. The impact increases with age and is stronger for women and in southern European countries. Conclusion Our estimates of informal care costs facilitate including informal care costs in CEAs of life-extending healthcare interventions. Including these costs may influence decisions as it leads to reranking of life-extending interventions compared with interventions improving quality of life.

Date: 2023
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DOI: 10.1007/s40273-022-01233-8

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