How Does Bereavement Affect the Health-Related Quality of Life of Household Members Who Do and Do Not Provide Unpaid Care? Difference-in-Differences Analyses Using the UK Household Longitudinal Survey

Becky Pennington (), Mónica Hernández Alava and Mark Strong
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Becky Pennington: University of Sheffield
Mónica Hernández Alava: University of Sheffield
Mark Strong: University of Sheffield

PharmacoEconomics, 2025, vol. 43, issue 4, No 3, 389-402

Abstract: Abstract Background Guidelines for modelling in economic evaluation recommend that it may be necessary to consider costs and outcomes until all modelled patients have died. Some guidelines also recommend that carers’ health-related quality of life (HRQoL) outcomes should be included. However, it is unclear whether economic evaluations should continue to include carers’ HRQoL after patients have died, and whether there is any evidence to support an additional bereavement effect for carers. Methods We used the UK Household Longitudinal Study waves 1–12. We used Difference-in-Differences to estimate the short- and long-term bereavement effects on the SF-6D for people who reported that they did and did not provide care to a household member who then died. We assumed parallel trends conditional on age, sex, long-term health conditions, education, and household income. Results Carers and non-carers experienced a significant loss in HRQoL in the year immediately following bereavement. Carers potentially experienced a loss in HRQoL in the year before bereavement, whereas the bereavement effect may have lasted longer for non-carers. For both groups, HRQoL became comparable to the non-bereaved population around 3 years after bereavement. Conclusions Bereavement has a statistically significant negative impact on HRQoL in the short-term, for both carers and non-carers. However, the effect size is small and is not sustained, suggesting that including bereavement in economic evaluation would make little difference to results.

Date: 2025
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DOI: 10.1007/s40273-024-01452-1

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