The Psychometric Properties of a Self-Administered, Open-Source Module for Valuing Metastatic Epidural Spinal Cord Compression Utilities

Markian Pahuta (), Aaron Frombach (), Emile Hashem (), Stewart Spence (), Christina Sun (), Eugene K. Wai (), Joel Werier (), Carl Walraven () and Doug Coyle ()
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Markian Pahuta: Henry Ford Health System
Aaron Frombach: The University of Ottawa
Emile Hashem: The University of Ottawa
Stewart Spence: The University of Ottawa
Christina Sun: The University of Ottawa
Eugene K. Wai: The Ottawa Hospital
Joel Werier: The Ottawa Hospital
Carl Walraven: University of Ottawa
Doug Coyle: University of Ottawa

PharmacoEconomics - Open, 2019, vol. 3, issue 2, No 8, 197-204

Abstract: Abstract Introduction Web surveys are often used for utility valuation. Typically, custom utility valuation tools that have not undergone psychometric evaluation are used. Objectives This study aimed to determine the psychometric properties of a metastatic epidural spinal cord compression (MESCC) module run on a customizable open-source, internet-based, self-directed utility valuation platform (Self-directed Online Assessment of Preferences [SOAP]). Methods Individuals accompanying patients to the emergency department waiting room in Ottawa, Canada, were recruited. Participants made SOAP MESCC health state valuations in the waiting room and 48 h later at home. Validity, agreement reliability, and responsiveness were measured by logical consistency of responses, smallest detectable change, the interclass correlation coefficient, and Guyatt’s responsiveness index, respectively. Results Of 285 participants who completed utility valuations, only 113 (39.6%) completed the re-test. Of these 113 participants, 92 (81.4%) provided valid responses on the first test and 75 (66.4%) provided valid responses on the test and re-test. Agreement for all groups of health states was adequate, since their smallest detectable change was less than the minimal clinically important difference. The mean interclass correlation coefficients for all health states were > 0.8, indicating at least substantial reliability. Guyatt’s responsiveness indices all exceeded 0.80, indicating a high level of responsiveness. Conclusions To our knowledge, this is the first validated open-source, web-based, self-directed utility valuation module. We have demonstrated the SOAP MESCC module is valid, reproducible, and responsive for obtaining ex ante utilities. Considering the successful psychometric validation of the SOAP MESCC module, other investigators can consider developing modules for other diseases where direct utility valuation is needed.

Date: 2019
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DOI: 10.1007/s41669-018-0092-1

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