The Costs of Industry-Sponsored Drug Trials in Canada

Dat T. Tran, Ilke Akpinar and Philip Jacobs ()
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Dat T. Tran: Institute of Health Economics
Ilke Akpinar: Institute of Health Economics
Philip Jacobs: University of Alberta

PharmacoEconomics - Open, 2020, vol. 4, issue 2, No 15, 353-359

Abstract: Abstract Objective The objective of this study was to estimate the provincial and nationwide costs of industry-sponsored drug clinical trials (CTs) in Canada. Methods We used the Aggregate Analysis of ClinicalTrials.gov (AACT) database, and included all industry-sponsored drug CTs that were conducted in Canada and completed in 2016. We estimated the costs of the study drugs using the market price. Estimates of the costs of management and patient services were based on industry contracts. Results The sample included 394 CTs that were conducted in 2039 facilities in Canada and provided services for 20,126 Canadian enrollees. Two-thirds of the CTs (277 of 394) were in the non-cancer category. On average, the drug costs per patient were 89,680 Canadian dollars ($Can) during the lifespan of the CTs, and were higher in cancer CTs than in non-cancer CTs ($Can216,876 vs. $Can65,274). The total costs of industry-sponsored drug CTs completed in 2016 was $Can2093.7 million. Drug costs accounted for the majority of this total ($Can1804.9 million). Ontario ($Can781.2 million) and Quebec ($Can757.5 million) had the highest costs. Conclusion The costs of industry-sponsored drug CTs completed in 2016 when measured in terms of market prices in Canada were valued at $Can2.1 billion.

Date: 2020
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DOI: 10.1007/s41669-019-0161-0

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