Bayesian prediction for two-stage sequential analysis in clinical trials

Hayet Merabet, Ahlam Labdaoui and Pierre Druilhet

Communications in Statistics - Theory and Methods, 2017, vol. 46, issue 19, 9807-9816

Abstract: This article deals with a Bayesian predictive approach for two-stage sequential analyses in clinical trials, applied to both frequentist and Bayesian tests. We propose to make a predictive inference based on the notion of satisfaction index and the data accrued so far together with future data. The computations and the simulation results concern an inferential problem, related to the binomial model.

Date: 2017
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DOI: 10.1080/03610926.2016.1222438

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