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Regression analysis of restricted mean survival time based on pseudo-observations for competing risks data

Xin Wang, Xiaoming Xue and Liuquan Sun

Communications in Statistics - Theory and Methods, 2018, vol. 47, issue 22, 5614-5625

Abstract: Competing risks data often occur in many medical follow-up studies. When the survival time is the outcome variable, the restricted mean survival time has heuristic and clinically meaningful interpretation. In this article, we propose a class of regression models for the restricted mean survival time in the competing risks setting. We adopt a technique of pseudo-observations to develop estimating equation approaches for the model parameters and establish asymptotic properties of the resulting estimators. The finite-sample behavior of the proposed method is evaluated through simulation studies, and an application to the Women’s Interagency HIV Study is provided.

Date: 2018
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DOI: 10.1080/03610926.2017.1397174

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