Tractable Model of Malignant Gliomas Immunotherapy with Discrete Time Delays

Monika Joanna Piotrowska, Marek Bodnar and Urszula Foryś

Mathematical Population Studies, 2014, vol. 21, issue 3, 127-145

Abstract: The model of an immune system reaction against malignant gliomas proposed by Kronik and co-workers is simplified to the main components of the immune reaction, which are tumor cells and cytotoxic T-lymphocytes. The system has nonlinear terms with three delays, but remains tractable. For realistic parameters, time delays have little influence on the dynamics.

Date: 2014
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DOI: 10.1080/08898480.2013.804690

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